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Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
August 9, 2007
Volume 19, No. 6

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Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Colorectal Adenomatous Polyposis Associated with MYH Mutations: Genotype and Phenotype Characteristics
Bouguen G, et al.
Dis Colon Rectum 2007 Aug

Comparisons of CYP2C19 Genetic Polymorphisms Between Korean and Vietnamese Populations
Lee SS, et al.
Ther Drug Monit 2007 Aug;29(4):455-9

 

Infectious and Parasitic Diseases

Association of polymorphism on HLA-DRB1*04 alleles with outcome of hepatitis B virus infection
Song M, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007 Aug;24(4):467-9

Extremes of l-ficolin concentration in children with recurrent infections are associated with single nucleotide polymorphisms in the FCN2 gene
Cedzynski M, et al.
Clin Exp Immunol 2007 Aug

 

Neoplasms

No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients
Petrova DT, et al.
J Cancer Res Clin Oncol 2007 Aug

Polymorphisms in DNA repair genes and risk of non-Hodgkin's lymphoma in New South Wales,Australia
Shen M, et al.
Haematologica 2007 Aug

High incidence of CTLA-4 AA (CT60) polymorphism in renal cell cancer
Cozar JM, et al.
Hum Immunol 2007 Aug;68(8):698-704

Joint Effects of the N-Acetyltransferase 1 and 2 (NAT1 and NAT2) Genes and Smoking on Bladder Carcinogenesis: A Literature-based Systematic HuGE Review and  Evidence Synthesis
Sanderson S, et al.
Am J Epidemiol 2007 Aug

5589del8: the recurrent mutation of BRCA1 gene in Chinese breast cancer patients
Hu Z, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007 Aug;24(4):378-81

Y chromosome haplogroups and susceptibility to testicular cancer
Ferlin A, et al.
Mol Hum Reprod 2007 Aug

TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population
Jin G, et al.
J Cancer Res Clin Oncol 2007 Aug

Polymorphic variants in alpha-methylacyl-CoA racemase and prostate cancer
Daugherty SE, et al.
Prostate 2007 Aug

Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine Eotaxin-1 in colorectal cancer patients
Wagsater D, et al.
World J Surg Oncol 2007 Jul;5(1):84

 

Endocrine, Nutritional and Metabolic Diseases

Association of Hind RFLP in lipoprotein lipase gene with type 2 diabetes
DU JK, et al.
Yi Chuan 2007 Aug;29(8):929-33

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
Lowe CE, et al.
Nat Genet 2007 Aug

TNFa microsatellite polymorphism modulates the risk of type 1 diabetes in the Belgian population, independent of HLA-DQ
Aminkeng F, et al.
Hum Immunol 2007 Aug;68(8):690-7

Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population
Maeda S, et al.
Kidney Int Suppl 2007 Aug(106):S43-8

Association between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and erectile dysfunction in patients with metabolic syndrome
Mazo EB, et al.
Int J Impot Res 2007 Aug

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
Lyssenko V, et al.
J Clin Invest 2007 Aug;117(8):2155-63

Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2  diabetes and related quantitative metabolic traits among 7088 Danish whites
Sparso T, et al.
Mol Genet Metab 2007 Aug

Epidemiology and genetic risk of type 1 diabetes among children in Aragon community, Spain
Soria J, et al.
Diabetes Res Clin Pract 2007 Aug

Heat-shock protein gene is not associated with type-1 diabetes in African Americans
Berka N, et al.
J Natl Med Assoc 2007 Jul;99(7):715-7

The CETP TaqIB Polymorphism is Associated with the Risk of Sudden Death in Type 2 Diabetic Patients
Porchay-Balderelli I, et al.
Diabetes Care 2007 Jul

 

Mental Disorders

Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: Association with HMG2L1 and TOM1
Potash JB, et al.
Am J Med Genet B Neuropsychiatr Genet 2007 Aug

Association study of the polymorphisms of monoamine oxidase A genes with schizophrenia
Shi Y, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007 Aug;24(4):457-9

Polymorphisms TaqI A of the DRD2, BalI of the DRD3, exon III repeat of the DRD4,  and 3' UTR VNTR of the DAT: Association with childhood ADHD in male African-Caribbean cocaine dependents?
Ballon N, et al.
Am J Med Genet B Neuropsychiatr Genet 2007 Aug

Polymorphisms of the dopamine d4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder
Shaw P, et al.
Arch Gen Psychiatry 2007 Aug;64(8):921-31

Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments
Palo OM, et al.
Hum Mol Genet 2007 Aug

Brain-derived neurotrophic factor (BDNF) gene not associated with antidepressant-induced mania
Zai G, et al.
Bipolar Disord 2007 Aug;9(5):521-5

Association of graded allele-specific changes in CYP2D6 function with imipramine  dose requirement in a large group of depressed patients
Schenk PW, et al.
Mol Psychiatry 2007 Jul

Association study of CSF2RB with schizophrenia in Irish family and case - control samples
Chen Q, et al.
Mol Psychiatry 2007 Jul

 

Diseases of the Nervous System and Sense Organs

Association study between gilles de la tourette syndrome and two genes in the robo-slit pathway located in the chromosome 11q24 linked/associated region
Miranda DM, et al.
Am J Med Genet B Neuropsychiatr Genet 2007 Aug

Genetic association studies of the chromosome 15 GABA-A receptor cluster in migraine with aura
Netzer C, et al.
Am J Med Genet B Neuropsychiatr Genet 2007 Aug

Environment-gene interaction in multiple sclerosis: Human herpesvirus 6 and MHC2TA
Martinez A, et al.
Hum Immunol 2007 Aug;68(8):685-9

The LOC387715 Polymorphism, Inflammatory Markers, Smoking, and Age-Related Macular Degeneration A Population-Based Case-Control Study
Wang JJ, et al.
Ophthalmology 2007 Jul

Support for an association of the C939T polymorphism in the human DRD2 gene with  tardive dyskinesia in schizophrenia
Mo GH, et al.
Schizophr Res 2007 Jul

 

Diseases of the Circulatory System

Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease
Breunis WB, et al.
Clin Exp Immunol 2007 Aug

USF1 Contributes to High Serum Lipid Levels in Dutch FCHL Families and U.S. Whites With Coronary Artery Disease
Lee JC, et al.
Arterioscler Thromb Vasc Biol 2007 Aug

Atrial natriuretic peptide gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension
Xue H, et al.
Clin Sci (Lond) 2007 Aug

389A/G polymorphism of the human beta 1-adrenergic receptor in patients with acute myocardial infarction
Song Y, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007 Aug;24(4):422-4

Relationship between Angiotensin-converting enzyme gene polymorphism and severity of aortic valve calcification
Ertas FS, et al.
Mayo Clin Proc 2007 Aug;82(8):944-50

Subarachnoid hemorrhage: tests of association with apolipoprotein E and elastin genes
Kaushal R, et al.
BMC Med Genet 2007 Jul;8(1):49

A prospective evaluation of apolipoprotein M gene T-778C polymorphism in relation to coronary artery disease in Han Chinese
Jiao GQ, et al.
Clin Biochem 2007 Jul

Combined effects of thrombosis pathway gene variants predict cardiovascular events
Auro K, et al.
PLoS Genet 2007 Jul;3(7):e120

Association of HLA DRB1-DQA1-DQB1 haplotypes with rheumatic heart disease in Taiwan
Chou HT, et al.
Int J Cardiol 2007 Jul

Relation between apolipoprotein CIII gene polymorphism and coronary artery disease
Liu SK, et al.
Zhonghua Yi Xue Za Zhi 2007 Apr;87(16):1133-5

 

Diseases of the Respiratory System

Transforming Growth Factor-{beta}1 C-509T Polymorphism, Oxidant Stress, and Early Onset Childhood Asthma
Salam MT, et al.
Am J Respir Crit Care Med 2007 Aug

85-kDa cytosolic phospholipase A(2) group IValpha gene promoter polymorphisms in  patients with severe asthma: a gene expression and case-control study
Sokolowska M, et al.
Clin Exp Immunol 2007 Aug

Association between RANTES polymorphisms and asthma severity among Tunisian children
Lachheb J, et al.
Hum Immunol 2007 Aug;68(8):675-80

A report of cytokine polymorphisms and COPD risk in Xuan Wei, China
Shen M, et al.
Int J Hyg Environ Health 2007 Jul

 

Diseases of the Digestive System

Association between genetic polymorphisms in thecyclooxygenase-1 gene promoter and peptic ulcers in Japan
Arisawa T, et al.
Int J Mol Med 2007 Sep;20(3):373-8

Combination of Helicobacter pylori strain and tumor necrosis factor-alpha polymorphism of the host increases the risk of peptic ulcer disease in children
Wilschanski M, et al.
J Pediatr Gastroenterol Nutr 2007 Aug;45(2):199-203

Replication of an Association Between IL23R Gene Polymorphism With Inflammatory Bowel Disease
Oliver J, et al.
Clin Gastroenterol Hepatol 2007 Aug;5(8):977-81.e2

Analysis of candidate genes on chromosomes 5q and 19p in celiac disease
Latiano A, et al.
J Pediatr Gastroenterol Nutr 2007 Aug;45(2):180-6

HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis
Nelson JE, et al.
Hepatology 2007 Aug

Genetic Susceptibility to Nonsteroidal Anti-Inflammatory Drug-Related Gastroduodenal Bleeding: Role of Cytochrome P450 2C9 Polymorphisms
Pilotto A, et al.
Gastroenterology 2007 Aug;133(2):465-71

 

Diseases of the Genitourinary System

The relationship of the peroxisome proliferator-activated receptor-gamma 2 exon 2 and exon 6 gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy
Erdogan M, et al.
Diabetes Res Clin Pract 2007 Aug

Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability,  and confer susceptibility to diabetic nephropathy
Kamiyama M, et al.
Hum Genet 2007 Aug

Correlation between CFTR Gene Mutations in Iranian Men with Congenital Absence of the Vas Deferens and Anatomical Genital Phenotype
Radpour R, et al.
J Androl 2007 Aug

 

Complications of Pregnancy, Childbirth, and the Puerperium

Immunogenetics of pregnancy: Role of a 14-bp deletion in the maternal HLA-G gene  in primiparous pre-eclamptic Brazilian women
Vianna P, et al.
Hum Immunol 2007 Aug;68(8):668-74

Association between 49 infant gene polymorphisms and preterm delivery
Chen BH, et al.
Am J Med Genet A 2007 Aug

Functional Variants of the Central Bile Acid Sensor FXR Identified in Intrahepatic Cholestasis of Pregnancy
van Mil SW, et al.
Gastroenterology 2007 Aug;133(2):507-16

Methylenetetrahydrofolate Reductase C677T Polymorphism and Pregnancy Complications
Stonek F, et al.
Obstet Gynecol 2007 Aug;110(2):363-8

 

Diseases of the Musculoskeletal System and Connective Tissue

[Association of single nucleotide polymorphisms of IL-1b with lumbar disc disease.]
Ye W, et al.
Yi Chuan 2007 Aug;29(8):923-8

Investigation of the IL23R gene in a Spanish rheumatoid arthritis cohort
Orozco G, et al.
Hum Immunol 2007 Aug;68(8):681-4

Association between the -1306C/T polymorphism of matrix metalloproteinase-2 gene  and lumbar disc disease in Chinese young adults
Dong DM, et al.
Eur Spine J 2007 Aug

A single tumor necrosis factor haplotype influences response to adalimumab in rheumatoid arthritis
Miceli-Richard C, et al.
Ann Rheum Dis 2007 Aug

Serum fasting cortisol in relation to bone, and the role of genetic variations in the glucocorticoid receptor
van Schoor NM, et al.
Clin Endocrinol (Oxf) 2007 Aug

The growth differentiation factor 5 (GDF5) core promoter polymorphism is not associated with knee osteoarthritis in the greek population
Tsezou A, et al.
J Orthop Res 2007 Aug

Associations between HLA, PTPN22, CTLA4 genotypes and RA phenotypes of autoantibody status, age at diagnosis, and erosions in a large cohort study
Karlson EW, et al.
Ann Rheum Dis 2007 Jul

 

 

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Page last reviewed: August 9, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics