DRAFT version February 12, 2008

Meeting of the Advisory Committee on Immunization Practices (ACIP) 
Centers for Disease Control and Prevention
1600 Clifton Road, NE, Tom Harkin Global Communications Center (Building 19), Atlanta, Georgia
February 27 – 28, 2008

Wednesday, February 27
8:00 am
Main topic: Welcome and Introductions
Presenters: Dr. Dale Morse (Chair, ACIP), Dr. Larry Pickering (Executive Secretary, ACIP; CDC)
 
8:30 am
Main Topic: Influenza Vaccines
Discussion items: Surveillance update, Vaccine strain selection and antiviral resistance, Vaccine effectiveness among 6-23 month old children, 2008-09 vaccination recommendations
Purpose: Information, Discussion, Vote, VFC Vote
Presenter: Dr. Anthony Fiore (CDC/NCIRD/ID), Dr. Alexander Klimov (CDC/NCIRD/ID), Dr. David Shay (CDC/NCIRD/ID), Dr. Kathleen Neuzil (ACIP, WG Chair), Dr. Gregory Wallace (CDC/NCIRD/ISD)

10:00am
Break

10:30am
Main Topic: Meningococcal Conjugate Vaccine (MCV4)
Discussion items: Overview of session and Working Group update, Burden of meningococcal disease among infants and children, Recommendations for general use of MCV4 among 2-10 year olds.
Purpose: Information, Discussion, Vote, VFC Vote
Presenters: Dr. Carol Baker (ACIP, WG Chair), Dr. Amanda Cohn (CDC/NCIRD/DBD), Dr. Gregory Wallace (CDC/NCIRD/ISD)

12:00pm
Lunch

1:00pm
Main Topic: Use of Vaccines during Pregnancy & Breastfeeding
Discussion items: Update on the activities of the ACIP Working Group on Vaccination during Pregnancy and Breastfeeding, Draft guiding principles for standardization of ACIP recommendations regarding vaccination during pregnancy and breastfeeding
Purpose: Information, Discussion
Presenter: Dr. Carol Baker (ACIP, WG Chair), Dr. Stephanie Schrag (CDC/NCIRD/DBD)

1:30
Main topic: Human Papillomavirus (HPV) Vaccines
Discussion items: Overview of session and Working Group update, Study on use of quadrivalent HPV vaccine in adult women (24-45 years of age), Update on bivalent HPV vaccine, Epidemiology of HPV infection in older women ,Cost effectiveness studies, Considerations for vaccination recommendations among women >26 years of age 
Purpose: Information, Discussion
Presenter: Dr. Janet Englund (ACIP, WG Chair), Dr. Richard Haupt (Merck), Dr. Gary Dubin (GSK), Dr. Eileen Dunne (CDC/NCHHSTP/DSTDP), Dr. Harrell Chesson (CDC/NCHHSTP/DSTDP), Dr. Lauri Markowitz (CDC/NCHHSTP/DSTDP)
3:00pm
Break

3:30pm
Main topic: Vaccine Safety Updates
Discussion items: Introduction, Overview of VSD rapid cycle analysis (RCA),  RCA results for MMRV (ProQuad®), Phase IV results for MMRV, Summary and conclusion 
Purpose: Information, Discussion
Presenter: Dr. John Iskander (CDC/OD/ISO), Dr. Tracy Lieu (ACIP, Harvard Pilgrim Health Care), Dr. Nicola Klein (Northern California Kaiser Permanente), Dr. Patricia Saddier (Epidemiology Group, Merck), Dr. John Iskander (CDC/OD/ISO) 

4:45pm
Main topic: Vaccine Supply
Purpose: Information, Discussion
Presenter: Dr. Greg Wallace (CDC/NCIRD/ISD)

5:15pm
Main topic: Public Comment

5:30pm
Adjourn

Thursday, February 28
8:00am
Main topic: Unfinished Business
Presenter: Dr. Dale Morse (Chair, ACIP)

8:30am
Main topic: Agency Updates (CDC/CCID/NCIRD/CMS, DOD, DVA, FDA, HRSA, HIS, NIH, NVPO)
Purpose: Information
Presenter: Dr. Dale Morse (Chair, ACIP)
 
8:45am
Main topic: Rotavirus Vaccines
Discussion items: Update from Rotavirus Vaccines Working Group, Working Group considerations and draft of proposed recommendations, Adoption of rotavirus vaccine by pediatric and family medicine physicians 
Purpose: Information, Discussion
Presenter: Dr. Lance Chilton (ACIP, WG Chair), Dr. Margaret Cortese (CDC/NCIRD/DVD), Ms. Shannan Stokley (CDC/NCIRD/ISD) 

9:45am
Main topic: Update: Implementation of Approach to Economic Analyses
Purpose: Information
Presenter: Dr. Tracy Lieu (ACIP Member, member of ACIP Ad Hoc Working Group on Economic Analyses)

9:50am
Main topic: Rabies Vaccines and Biologicals
Discussion items: Update on supply of rabies vaccines and biologicals 
Purpose: Information, Discussion
Presenter: Dr. Charles Rupprecht (CDC/NCZVED/DVRD)

10:10am
Main topic: Update: General Recommendations
Purpose: Information, Discussion
Presenter: Dr. Ciro Sumaya (ACIP, WG Chair), Dr. Andrew Kroger (CDC/NCIRD/ISD)

10:30am
Break

10:45am
Main topic:  Japanese Encephalitis Vaccines
Discussion items: Update from Japanese Encephalitis (JE) Vaccines Working Group, 
JE vaccine for U.S. travelers, JE vaccine availability in the U.S., A new inactivated cell culture-derived JE vaccine for adult travelers, Questions and discussion 
Purpose:  Information, Discussion
Presenter: Dr. Patsy Stinchfield (ACIP, WG Chair), Dr. Marc Fischer (CDC/NCZVED/DVBID), Mr. Phil Hosbach (sanofi pasteur), Dr. Erich Tauber (Intercell)

11:45am
Main topic:  Anthrax Vaccines
Discussion items: Introduction, Background information on anthrax vaccine, Data from recent publications, Presentation of data on anthrax vaccine from the Anthrax Vaccine Research Program’s on going clinical trial, Items for consideration 
Purpose:  Information
Presenter: Dr. Dale Morse (ACIP, WG Chair), Dr. Jennifer Wright (CDC/NCIRD/DBD), COL. Ted Cieslak (Department of Defense),  Dr. Conrad Quinn (CDC/NCIRD/DBD),  

1:10pm
Main topic: Public Comment

1:30pm
Adjourn

Acronyms used in this agenda:
Advisory Committee on Immunization Practices (ACIP)
Coordinating Center for Infectious Diseases (CCID)
Centers for Disease Control & Prevention (CDC)
Centers for Medicare and Medicaid Services (CMS)
Division of Bacterial Diseases (DBD, of NCIRD)
Department of Defense (DOD)
Division of Sexually Transmitted Diseases Prevention (DSTDP of NCHHSTP)
Department of Veterans Affairs (DVA)
Division of Viral Diseases (DVD, of NCIRD)
Division of Viral Hepatitis (DVH, of NCHHSTP)
Food and Drug Administration (FDA)
Health Resources and Services Administration (HRSA)
Influenza Division (ID, of NCIRD)
Indian Health Service (HIS)
Immunization Services Division (ISD, of NCIRD)
Immunization Safety Office (ISO, of CDC/OD/Office of the Chief Science Officer)
National Center for HIV, Hepatitis, STD and TB Prevention (NCHHSTP, of CDC/CCID)
CDC National Center for Immunization & Respiratory Diseases (NCIRD, of CDC/CCID) 
National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID)
National Center for Zoonotic, Vector-Borne, and Enteric Diseases (NCZVED, of CDC/CCID)
National Institutes of Health (NIH)
National Vaccine Advisory Committee (NVAC)
National Vaccine Program Office (NVPO)
Office of the Chief Science Officer (OCSO, of OD)
Office of the Director (OD, of CDC)
To be determined (TBD)
Work Group (WG)

This document can be found on the CDC website at:
http://www.cdc.gov/vaccines/recs/acip/downloads/agenda-feb08.rtf