Laboratory of Pharmacology - Publications

• Miller DS, Bauer B and Hartz AMS (InPress) Modulation of P-glycoprotein at the blood-brain barrier: Opportunities to improve CNS pharmacotherapy., Pharmacol.

• Hartz AMS, Bauer B, Block ML, Hong J-S and Miller DS (InPress) Diesel exhaust particles induce oxidative stress, pro-inflammatory signaling, and P-glycoprotein upregulation at the blood-brain barrier, FASEB.

• Bauer B, Hartz AM, Yang X, Lucking, JR, Pollack GM, Fricker G, Miller DS (2008) Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTÀ, at the blood-brain barrier, J Cerebral Blood Flow Metab 28, 1222-1234.

• Bauer B, Hartz AM, Pekcec A, Toellner K, Miller DS, Potschka H. (2008) Seizure-induced upregulation of P-glycoprotein at the blood-brain barrier through glutamate and COX-2 signaling, Mol Pharm 73, 329-41.

• Bauer, B., Hartz, A.M.S., and Miller D.S (2007) TNF-a and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier, Mol. Pharm 71, 667-75.

• Bauer B, Yang X, Hartz AM, Olson ER, Zhao R, Kalvass JC, Pollack GM, Miller DS (2006) In vivo activation of human PXR tightens the blood-brain barrier to methadone through P-glycoprotein upregulation, Mol Pharm 70, 1212-1219.