Neuron-Glia Interactions: Their Mechanisms and Their Roles in Development and Disease

 


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Air date: Monday, September 10, 2007, 12:00:00 PM
Category: Neuroscience
Runtime: 75 minutes
NLM Title: Neuron-glia interactions : their mechanisms and their roles in development and disease [electronic resource] / Gabriel Corfas.
Series: NIH neuroscience seminar series
Author: Corfas, Gabriel.
National Institutes of Health (U.S.)
Publisher: [Bethesda, Md. : National Institutes of Health, 2007]
Other Title(s): NIH neuroscience seminar series
Abstract: (CIT): Dr. Corfas is interested in understanding the molecular signals that regulate neuron-glia interactions, which play critical roles in several aspects of nervous-system development, including neuronal migration, neuronal and glial differentiation and survival, and the formation and function of synapses. To this end, his research employs molecular and cellular biological techniques, as well as genetically modified mice. One aspect of Dr. Corfas' work focuses on the growth factor neuregulin (NRG) and its erbB receptors, key mediators of neuron-glia interactions. He and his colleagues have found that these molecules mediate interactions between migrating neurons and the radial glial fibers along which they migrate during the development of the central nervous system, and between several types of glia and neurons in the adult nervous system.
Subjects: Nervous System Physiological Phenomena
Neuroglia--physiology
Publication Types: Government Publications
Lectures
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NLM Classification: WL 102
NLM ID: 101317970
CIT File ID: 14012
CIT Live ID: 6161
Permanent link: http://videocast.nih.gov/launch.asp?14012

 

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