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NINDS Meningitis and Encephalitis Information Page

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Synonym(s):   Meningitis, Encephalitis
Condensed from Meningitis and Encephalitis Fact Sheet

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What are Meningitis and Encephalitis?

Meningitis and encephalitis are inflammatory diseases of the membranes that surround the brain and spinal cord and are caused by bacterial or viral infections. Viral meningitis is sometimes called aseptic meningitis to indicate it is not the result of bacterial infection and cannot be treated with antibiotics. Symptoms of encephalitis include sudden fever, headache, vomiting, heightened sensitivity to light, stiff neck and back, confusion and impaired judgment, drowsiness, weak muscles, a clumsy and unsteady gait, and irritability. Symptoms that might require emergency treatment include loss of consciousness, seizures, muscle weakness, or sudden severe dementia.

Symptoms of meningitis, which may appear suddenly, often include high fever, severe and persistent headache, stiff neck, nausea, and vomiting. Changes in behavior such as confusion, sleepiness, and difficulty waking up may also occur. In infants, symptoms of meningitis may include irritability or fatigue, lack of appetite, and fever. Viral meningitis usually resolves in 10 days or less, but other types of meningitis can be deadly if not treated promptly. Anyone experiencing symptoms of meningitis or encephalitis should see a doctor immediately.

Is there any treatment?

Antiviral medications may be prescribed for herpes encephalitis or other severe viral infections. Antibiotics may be prescribed for bacterial infections. Anticonvulsants are used to prevent or treat seizures. Corticosteroids are used to reduce brain swelling and inflammation. Sedatives may be needed for irritability or restlessness. Over-the-counter medications may be used for fever and headache. Individuals with encephalitis or bacterial meningitis are usually hospitalized for treatment.

What is the prognosis?

The prognosis for encephalitis varies. Some cases are mild, short and relatively benign and patients have full recovery. Other cases are severe, and permanent impairment or death is possible. The acute phase of encephalitis may last for 1 to 2 weeks, with gradual or sudden resolution of fever and neurological symptoms. Neurological symptoms may require many months before full recovery. With early diagnosis and prompt treatment, most patients recover from meningitis. However, in some cases, the disease progresses so rapidly that death occurs during the first 48 hours, despite early treatment.

What research is being done?

The NINDS supports and conducts research on infections and diseases of the brain and nervous system including encephalitis and meningitis. Much of this research is aimed at learning more about the cause(s), prevention, and treatment of these disorders.

More info

NIH Patient Recruitment for Meningitis and Encephalitis Clinical Trials

Organizations

Meningitis Foundation of America, Inc.
6610 Shadeland Station
Suite 200
Indianapolis, IN   46220
support@musa.org
http://www.musa.org
Tel: 800-668-1129 317-595-6395
Fax: 317-595-6370

 National Meningitis Association
738 Robinson Farms Drive
Marietta, GA   30068
support@nmaus.org
http://www.nmaus.org
Tel: 866-FONE-NMA (366-3662)
Fax: 877-703-6096
National Institute of Allergy and Infectious Diseases (NIAID)
National Institutes of Health, DHHS
6610 Rockledge Drive, MSC 6612
Bethesda, MD   20892-6612
http://www.niaid.nih.gov
Tel: 301-496-5717

  
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Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892



NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.

All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.

Last updated December 11, 2007