| Investigator:
Edward Giniger
Affiliation: Axon
Guidance and Neural Connectivity Unit, NINDS, NIH, Department of
Health and Human Services
Position Type: Postdoctoral
Fellowship
Labs Web Page: http://neuroscience.nih.gov/Lab.asp?Org_ID=91
Description:
Postdoctoral positions are
available for creative, independent scientists interested in studying axon guidance in
Drosophila. We are investigating the mechanism of a non-canonical signaling pathway by
which the cell surface receptor, Notch, directly controls axon growth and guidance by
regulating the cortical actin cytoskeleton via the Abl tyrosine kinase and Rac GTPase.
We employ a combination of classical and molecular genetics, biochemistry and advanced
in vivo imaging techniques. A second focus is the molecular mechanism responsible for
ensuring the accuracy of neural wiring. This work centers on how the cyclin-dependent
kinase Cdk5 coordinates the action of different signaling pathways in the growth cone,
and also on why improper regulation of this kinase causes adult-onset neurodegenerative
disease in both flies and mammals.
Application
Instructions:
Please send a letter
or email describing your research interests and long-term goals, a CV and the names of
3 references to:
Dr Edward Giniger, PhD
Axon Guidance and Neural Connectivity Unit, NINDS, NIH
Bldg 49, Rm 3A18
49 Convent Dr, MSC 4478
Bethesda, MD 20892-4478
Phone: 301-451-3891
Email: ginigere@ninds.nih.gov
NIH AND DHHS ARE EQUAL OPPORTUNITY EMPLOYERS
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