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Advanced MRI Section
Jeff H. Duyn, Ph.D., Investigator
Dr. Duyn received his M.Sc. and Ph.D. degrees in physics at the University of Delft, Holland where he was involved with the development of X-ray diffraction techniques, as well as the early development of magnetic resonance imaging (MRI). During his postdoctoral assignments at the University of California, San Francisco, and at NIH, his research focused on the study of human brain physiology, as measured by spectroscopic and functional MRI techniques. Dr. Duyn moved to NINDS in 2000.
Staff:
- Jacco A de Zwart, Ph.D., Staff Scientist, 301-594-7315 dezwartj @ mail.nih.gov
- Masaki Fukunaga, Ph.D., Visiting Fellow, 301-594-7312 fukunagm @ mail.nih.gov
- Susan C Fulton, Medical Technologist, 301-451-9912 oflahavs @ mail.nih.gov
- Silvina G Horovitz, Ph.D., Research Fellow horovits @ mail.nih.gov
- J Martijn Jansma, Ph.D., Postdoctoral Fellow, 301-451-9919 jansmam @ mail.nih.gov
- Lei Qin, Special Volunteer, 301-451-9917 qinl @ mail.nih.gov
- Karin Shmueli, Ph.D., Visiting Fellow, 301-451-9916 shmuelik @ mail.nih.gov
- Peter van Gelderen, Ph.D., Staff Scientist, 301-402-1472 gelderen @ helix.nih.gov
Research Interests:
In addition to providing structural information, MRI has the potential to non-invasively map physiologic parameters and function. The current research focus is to optimally exploit this potential by investigating the mechanisms behind MRI contrast, exploring avenues to manipulate the contrast, and optimizing MRI data acquisition and analysis to achieve optimum sensitivity, resolution, reliability, and accuracy. Specific aims are the development of MRI techniques for the measurements of structural anatomy, tissue metabolism, tissue perfusion, and blood oxygenation level dependent contrast in both normal and diseased human brain.
Website of the Advanced MRI section of LFMI: http://www.amri.ninds.nih.gov/
Website of the Laboratory of Functional and Molecular Imaging: http://www.lfmi.ninds.nih.gov/
Selected Publications:
- F.J. Langheim, J.H. Callicott, V.S. Mattay, J.H. Duyn, D.R. Weinberger (2002) Cortical Systems Associated with Covert Music Rehearsal, NeuroImage 16 (4), 901-8.
- M.N. Yongbi, F. Fera, J.A. Frank, V.S. Mattay, J.H. Duyn (2002) Comparison of Multi-Slice Baseline and fMRI Perfusion Signal at 1.5T and 3.0T Using Pulsed Arterial Spin Labeling: Initial Results in Six Subjects, Radiology 222, 569-575.
- E.L. Barbier, S. Marrett, A. Danek, A. Vortmeyer, P. van Gelderen, J. Duyn, P. Bandettini, J. Grafman, A.P. Koretsky (2002) Imaging Cortical Anatomy by High Resolution MR at 3.0T: Detection of the Stripe of Gennari in Visual Area 17, Magn. Resonance Med. 48 (4), 738-8.
- G. Tedeschi, S. Bonavita, H.F. McFarland, N. Richert, J.H. Duyn, J.A. Frank (2002) Proton MR Spectroscopic Imaging in Multiple Schlerosis, Neuroradiology 44 (1), 37-42.
- J.A. de Zwart, P. van Gelderen, P. Kellman, J.H. Duyn (2002) Application of Sensitivity-Encoded Echo-Planar Imaging for Blood Oxygen Level-Dependent Functional Brain Imaging, Magn. Resonance Med. 48 (6), 1011-20.
- J.A. de Zwart, P. van Gelderen, P. Kellman, J.H. Duyn (2002) Reduction of Gradient Acoustic Noise in MRI Using SENSE-EPI, NeuroImage 16 (4), 1151-5.
- J.A. de Zwart, P.J. Ledden, P. Kellman, P. van Gelderen, J.H. Duyn (2002) Design of a SENSE-Optimized High-Sensitivity MRI Receive Coil for Brain Imaging, Magn. Resonance Med. 47 (6), 1218-27.
All Selected Publications
Contact Information:
Dr. Jeff H. Duyn
Advanced MRI Section
Laboratory of Functional and Molecular Imaging, NINDS
Building 10, Room B1D724
10 Center Drive, MSC 1065
Bethesda, MD 20892-1065
Telephone: 301-594-7305 office,
301-594-7305 laboratory,
301-594-7315 fax
Email: jhd@helix.nih.gov
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