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Russell Lonser, M.D., Investigator

Dr. Lonser received his M.D. from Loma Linda University Medical School in 1994 and completed his Neurological Surgery residency training at the University of Utah in 2001. During his residency training, he spent over 2 years performing research in the Surgical Neurology Branch (1995 to 1998). He returned to the Surgical Neurology Branch in 2001 as a Staff Clinician. He was awarded the Tumor Young Investigator Award in 2002 from the American Association of Neurological Surgeons and Congress of Neurological Surgeons. He is Chair of the Surgical Neurology Branch in NINDS. His laboratory studies drug delivery for treatment of neurologic disorders, as well as investigates tumor biology and treatment.
Photo of Russell Lonser, M.D., Investigator

Staff:



Clinical Protocols:
  • Genetic Analysis of the Chiari I Malformation ( 00-N-0089 )
  • Establishing the Pathophysiology of Primary Spinal Syringomyelia ( 01-N-0085 )
  • A Prospective Natural History Study of VHL Patients with CNS Hemangioblastomas ( 00-N-0140 )
  • Evaluation of the Mechanism of NO Formation and Pharmacokinetics of Long-term Intravenous Nitrite Infusion in Healthy Volunteers ( 05-N-0075 )
  • Assessment of cerebral circulation and perfusion in adults after neonatal carotid occlusion ( 08-N-0095 )
  • Establishing the Physiology of Syringomyelia ( 92-N-0226 )
  • Evaluation and Treatment of Neurosurgical Disorders ( 03-N-0164 )
  • A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2) ( 08-N-0044 )
  • Trial of Intracerebral Infusion in Patients with Medically Intractable Epilepsy ( 00-N-0158 )
  • Two-Compartment Model of Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) for the Diagnosis of Glioma Tumor Recurrence versus Radiation Necrosis ( 06-N-0085 )

Selected Recent Publications:
  • Lonser RR, Schiffmann R, Robison RA, Butman JA, Quezado Z, Walker ML, Morrison PF, Walbridge S, Murray G, Park DM, Brady RO, Oldfield EH (2007) Image-guided direct convective delivery of glucocerebrosidase for neuronopathic Gaucher disease, Neurology 68, 254-261.

  • Butman JA, Kim HJ, Baggenstos M, Ammerman JM, Patsalides A, Patronas NJ, Oldfield EH, Lonser RR (2007) Mechanisms of morbid hearing loss associated with tumors of the endolymphatic sac in von Hippel-Lindau disease, JAMA 298, 41-48.

  • Park DM, Zhuang Z, Chen L, Maric I, Sohn T, Kim SH, Lubensky IA, Rodgers GP, Oldfield EH, Lonser RR (2007) VHL-associated hemangioblastomas derive from embryologic multipotent cells, PLoS Medicine 4, 333-341.

  • Murad GJA, Walbridge S, Degen JW, Morrison PF, Brechbiel M, Garmestani K, Oldfield EH, Lonser RR (2006) Real-time, image-guided, convection-enhanced delivery of interleukin 13 bound to Pseudomonas exotoxin, Clin Cancer Res 12, 3145-3151.

  • Lonser RR, Vortmeyer AO, Butman JA, Glasker S, Finn MA, Ammerman JM, Merrill MJ, Edwards NA, Zhuang Z, Oldfield EH (2005) Edema is a precursor to central nervous system peritumoral cyst formation, Ann Neurol 58, 392-399.

  • Weil RJ, Lonser RR (2005) Selective excision of metastatic brain tumors originating in the motor cortex with preservation of function, J Clin Oncol 23, 1209-1217.

  • Lonser RR, Walbridge S, Murray GJ, Aizenberg MR, Vortmeyer AO, Aerts JMFG, Brady RO, Oldfield EH (2005) Convection perfusion of glucocerebrosidase for neuronopathic Gaucher's disease, Ann Neurol 57, 542-548.

All Selected Publications


Contact Information:

Dr. Russell Lonser
National Institute of Neurological Disorders and Stroke
National Institutes of Health
10 Center Drive
Building 10, Room 5D37
Bethesda, MD 20892-1414

Telephone: (301) 496-5728 (office), (301) 496-5728 (laboratory), (301) 402-0380 (fax)
Email: lonserr@mail.nih.gov

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Last updated Tuesday, December 23, 2008