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| Wayne C. Drevets, M.D., Senior Investigator |
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Dr. Drevets received his B.S. in Biology from Wheaton College and his M.D. degree from the University of Kansas. He joined the Department of Psychiatry at Washington University Medical School where he rose to the rank of tenured Associate Professor. During these years he conducted positron emission tomography (PET) imaging studies of mood and anxiety disorders under the mentorship of Dr. Marcus Raichle. He moved to the University of Pittsburgh, where he continued to study brain imaging and acquired additional training in the application of PET to receptor imaging. In 2001, Dr. Drevets joined the NIMH Mood and Anxiety Disorders Program as a Senior Investigator. He is currently involved in research employing PET and MRI technologies to better understand mood and anxiety disorders.
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Staff:
- Ms. Dari-Lee Barnes, Secretary, (301) 402-1471 barnesd@intra.nimh.nih.gov
- Dr. Dara Cannon, Ph.D., Postdoctoral Fellow, (301) 496-4541 cannond@intra.nimh.nih.gov
- Dr. Paul Carlson, M.D., Clinical Fellow, (301) 402-7976 carlsonp@mail.nih.gov
- Dr. Kristine Erickson, Ph.D., Investigator, (301) 594-1428 ericksok@intra.nimh.nih.gov
- Dr. Maura Furey, Ph.D., Staff Scientist, (301) 594-7773 mfurey@mail.nih.gov
- Dr. Girma Hawariat, Ph.D., Special Expert, (301) 402-8039 hawariag@intra.nimh.nih.gov
- Ashish Khanna, B.A., Post baccalaureate Fellow, (301) 451-1161 khannaa@mail.nih.gov
- Jackie Klaver, B.A., Post baccalaureate Fellow, (301) 594-4664 klaverj@mail.nih.gov
- Dr. Jamey Levy, Ph.D., Postdoctoral Fellow, (301) 496-0770 jamey@mail.nih.gov
- Dr. Chantal Martin-Soelch, Ph.D., Postdoctoral Fellow, (301) 496-4542 martinsoelchc@mail.nih.gov
- Dr. Allison Carol Nugent, Ph.D., Staff Scientist, (301) 594-1090 nugenta@intra.nimh.nih.gov
- Joanna Szczepanik, B.A., Research Assistant, (301) 594-9287 szczepaj@mail.nih.gov
- Ruth Tinsley, B.A., Post baccalaureate Fellow, (301) 451-9797 tinsleyr@mail.nih.gov
- Dr. Hongye Wang, Ph.D., Postdoctoral Fellow, (301) 594-1429 hongye@mail.nih.gov
Research Interests:
The Mood and Anxiety Disorders Imaging Section consists of a multidisciplinary team, which applies functional, and structural neuroimaging measures to investigate the biological mechanisms of normal and pathological emotional states. Multimodal imaging studies in which subject samples are studied using various imaging techniques are conducted in order to provide complementary information about pathophysiology. Positron emission tomography (PET), functional magnetic resonance imaging (fMRI), magnetic resonance spectroscopy (MRS) and morphological MRI are iteratively applied to investigate abnormalities of function or structure in mood and anxiety disorders. Areas of concentration include: 1) investigating the anatomical, neurophysiological and neurochemical substrates of normal emotional expression, evaluation, learning or experience, 2) characterizing the anatomical and neurochemical systems involved in modulating emotional responses, and assessing how these systems function in mood and anxiety disorders, 3) examining the effects of psychotropic medications on brain structure and function in adults with mood and anxiety disorders, 4) assessing the receptor pharmacology of mood and anxiety disorders using a variety of newly developed PET radioligands, 5) distinguishing abnormalities that are trait-like and stable across mood states from those that are mood-state dependent, and 6) delineating phenotypic differences between major depressive subtypes in order to refine the nosology of mood disorders.
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Selected Recent Publications:
Cannon DM, Carson RE, Nugent AC, Eckelman WC, Kiesewetter DO, Williams J, Rollis D, Drevets M, Gandhi SK, Solorio G, Drevets WC. (2006) Reduced Muscarinic Type II Receptor Binding in Depressed Subjects with Bipolar Disorder, Archives of general Psychiatry.
Drevets WC, Gautier CH, Price JC, Kupfer DJ, Kinahan PE, Grace AA, Price JL, Mathis CA (2001) Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria, Biol. Psychiatry 49, 81-96.
All Selected Publications
Contact Information:
Dr. Wayne C. Drevets
Neuroimaging Section
Mood and Anxiety Disorders Program, NIMH
Building 15K, Room 203
15 North Drive MSC 2070
Bethesda, MD 20892-2070
Telephone: (301) 594-1367 (office),
(301) 594-9959 (fax)
Email: drevetsw@INTRA.NIMH.NIH.GOV
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