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| Elisabeth A. Murray, Ph.D., Senior Investigator |
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Dr. Murray received her B.S. from Bucknell University and her Ph.D. from the University of Texas Medical Branch at Galveston, where she studied the organization of corticospinal neurons. After postdoctoral work at the NIMH with Mort Mishkin studying the neural substrates of tactual learning and memory, she became a Staff Fellow and then a tenured faculty member within the Laboratory of Neuropsychology, NIMH. Dr. Murray was awarded the Demuth Swiss Medical Research Foundation Award for Young Investigators in the Neurosciences and a PHS Special Recognition Award. Dr. Murray's laboratory is studying the neural basis of learning and memory, including how object and spatial perceptions in the different sensory modalities are formed into memories, how they evoke emotions and motor acts, and how the stored information may be used to plan future actions.
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Staff:
- Dawn Anuszkiewicz-Lundgren, B.S., Research Assistant, (301) 443-8630 lundgrend@mail.nih.gov
- Ping-Yu Chen, B.S., Research Assistant, (301) 443-7681 pingyuchen@mail.nih.gov
- Daniel P Gorrin, B.A., Postbaccalaureate IRTA gorrind@mail.nih.gov
- Emily J Howland, B.A., Postbaccalaureate IRTA howlande@mail.nih.gov
- Sarah EV Rhodes, Ph.D., Fogarty Postdoctoral Fellow sarah.rhodes@mail.nih.gov
- Peter H Rudebeck, D.Phil., Fogarty Postdoctoral Fellow rudebeckp@mail.nih.gov
- Susheel Vijayraghavan, Ph.D., Postdoctoral Fellow vijayraghavans@mail.nih.gov
Research Interests:
The aim of my research program is to understand how information about objects and events is stored in the brain, how object representations are linked with one another to mediate associative memories and associative recall, and how object representations are linked to reward, emotion and to action. Recent work has addressed three main themes: (1) how the brain uses cognitive and affective information to guide decision making and response selection; (2) how the inferotemporal cortex, especially perirhinal cortex, contributes to visual perception and memory; and (3) the role of the hippocampus in spatial and nonspatial learning. The work makes use of selective cerebral lesions and disconnections, and takes advantage of state-of-the-art techniques, including MRI-guided stereotaxic surgery combined with injection of excitotoxins, and injection of receptor-targeted DNA constructs.
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Selected Recent Publications:
Murray EA, Bussey TJ, and Saksida LM (2007) Visual perception and memory: a new view of medial temporal lobe function in primates and rodents, Annual Review of Neuroscience 30, 99-122.
Murray, EA (2007) The amygdala, reward and emotion, Trends in Cognitive Sciences 11, 489-497.
Murray EA, Izquierdo A (2007) Orbitofrontal cortex and amygdala contributions to affect and action , New York Academy of Sciences 1121, 273-296.
Brasted PJ, Bussey TJ, Murray EA, and Wise SP (2005) Conditional motor learning in the nonspatial domain: effects of errorless learning and the contribution of the fornix to one-trial learning, Behav Neurosci 119, 662-676.
Barense MD, Bussey TJ, Lee ACH, Rogers TT, Davies RR, Saksida LM, Murray EA, and Graham KS (2005) Functional specialization in the human medial temporal lobe, J Neurosci 25, 10239-10246.
Murray EA, and Wise SP (2004) What, if anything, is the medial temporal lobe, and how can the amygdala be part of it if there is no such thing?, Neurobiology of Learning and Memory 82, 178-198.
Baxter MG and Murray EA (2002) The amygdala and reward, Nat Rev Neurosci 3, 563-73.
Full Text/Abstract
All Selected Publications
Contact Information:
Dr. Elisabeth A. Murray
Section on the Neurobiology of Learning & Memory
Laboratory of Neuropsychology, NIMH
Building 49, Room lB80
49 Convent Drive MSC 4415
Bethesda, MD 20892-4415
Telephone: (301) 443-7401 (office),
(301) 402-0046 (fax)
Email: murraye@mail.nih.gov
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