Explanation of Figures, Section 5: Trends in ART, 1996–2004

Figure 45: Is the use of ART increasing?

Figure 45 is a line graph representing the number of ART cycles performed, number of live-birth deliveries, and number of infants born using ART, by year from 1996 to 2004.

• 1996: 64,681 ART cycles, 14,507 live-birth deliveries, 20,840 infants born.
• 1997: 72,397 ART cycles, 17,186 live-birth deliveries, 24,785 infants born.
• 1998: 81,438 ART cycles, 20,126 live-birth deliveries, 28,851 infants born.
• 1999: 87,636 ART cycles, 21,746 live-birth deliveries, 30,629 infants born.
• 2000: 99,629 ART cycles, 25,228 live-birth deliveries, 35,025 infants born.
• 2001: 107,587 ART cycles, 29,344 live-birth deliveries, 40,687 infants born.
• 2002: 115,392 ART cycles, 33,141 live-birth deliveries, 45,751 infants born.
• 2003: 122,872 ART cycles, 35,785 live-birth deliveries, 48,756 infants born.
• 2004: 127,977 ART cycles, 36,760 live-birth deliveries, 49,458 infants born.
   

Figure 46 is a line graph representing live births per transfer, by type of ART cycle, and by year from 1996 to 2004.

• 1996: Fresh–nondonor 28.0%, Frozen–nondonor 16.7%, Fresh–donor 38.9%,
  Frozen–donor 20.8%
• 1997: Fresh–nondonor 29.7%, Frozen–nondonor 18.8%, Fresh–donor 39.8%,
  Frozen–donor 22.3%
• 1998: Fresh–nondonor 30.9%, Frozen–nondonor 19.4%, Fresh–donor 40.8%,
  Frozen–donor 23.3%
• 1999: Fresh–nondonor 31.3%, Frozen–nondonor 18.6%, Fresh–donor 41.7%,
  Frozen–donor 24.0%
• 2000: Fresh–nondonor 31.6%, Frozen–nondonor 20.3%, Fresh–donor 43.5%,
  Frozen– donor 23.9%
• 2001: Fresh–nondonor 33.4%, Frozen–nondonor 23.4%, Fresh–donor 47.0%,
  Frozen– donor 27.3%
• 2002: Fresh–nondonor 34.8%, Frozen–nondonor 24.8%, Fresh–donor 50.0%,
  Frozen– donor 28.8%
• 2003: Fresh–nondonor 34.7%, Frozen–nondonor 27.0%, Fresh–donor 50.8%,
  Frozen– donor 30.1%
• 2004: Fresh–nondonor 34.0%, Frozen–nondonor 27.7%, Fresh–donor 50.5%,
  Frozen– donor 30.5%

Figure 47: Are singleton live birth rates improving?

Figure 47 is a line graph representing singleton live births per transfer, by type of ART cycle, and by year from 1996 to 2004.

• 1996: Fresh–nondonor 17.2%, Frozen–nondonor 12.2%, Fresh–donor 22.7%,
  Frozen–donor 15.3%
• 1997: Fresh–nondonor 18.2%, Frozen–nondonor 14.0%, Fresh–donor 22.1%,
  Frozen–donor 14.7%
• 1998: Fresh–nondonor 19.1%, Frozen–nondonor 14.1%, Fresh–donor 22.9%,
  Frozen–donor 16.8%
• 1999: Fresh–nondonor 19.7%, Frozen–nondonor 13.5%, Fresh–donor 24.3%,
  Frozen–donor 16.7%
• 2000: Fresh–nondonor 20.5%, Frozen–nondonor 15.1%, Fresh–donor 25.8%,
  Frozen–donor 16.9%
• 2001: Fresh–nondonor 21.4%, Frozen–nondonor 17.2%, Fresh–donor 27.4%,
  Frozen–donor 19.6%
• 2002: Fresh–nondonor 22.5%, Frozen–nondonor 18.7%, Fresh–donor 28.8%,
  Frozen–donor 20.9%
• 2003: Fresh–nondonor 22.8%, Frozen–nondonor 20.2%, Fresh–donor 30.3%,
  Frozen–donor 22.3%
• 2004: Fresh–nondonor 23.0%, Frozen–nondonor 21.0%, Fresh–donor 30.3%,
  Frozen–donor 22.5%

Figure 48: Are live birth rates improving for all ART patients or only for those in particular age groups?

Figure 48 is a line graph representing live births per transfer for ART cycles using fresh nondonor eggs or embryos, by woman’s age, and by year from 1996 to 2004.

• 1996: Age <35, 33.6%; Age 35–37, 29.0%; Age 38–40, 21.6%; Age 41–42, 11.5%;
  Age >42, 5.4%
• 1997: Age <35, 35.9%; Age 35–37, 31.4%; Age 38–40, 22.5%; Age 41–42, 13.3%;
  Age >42, 6.1%
• 1998: Age <35, 37.4%; Age 35–37, 31.9%; Age 38–40, 23.6%; Age 41–42, 14.1%;
  Age >42, 6.9%
• 1999: Age <35, 37.8%; Age 35–37, 32.4%; Age 38–40, 24.2%; Age 41–42, 13.6%;
  Age >42, 7.2%
• 2000: Age <35, 38.4%; Age 35–37, 33.0%; Age 38–40, 24.34%; Age 41–42, 14.3%;
  Age >42, 6.0%
• 2001: Age <35, 41.1%; Age 35–37, 35.1%; Age 38–40, 25.4%; Age 41–42, 14.5%;
  Age >42, 6.7%
• 2002: Age <35, 43.0%; Age 35–37, 37.1%; Age 38–40, 26.4%; Age 41–42, 14.7%;
  Age >42, 6.6%
• 2003: Age <35, 43.2%; Age 35–37, 36.6%; Age 38–40, 26.1%; Age 41–42, 15.1%;
  Age >42, 5.9%
• 2004: Age <35, 42.7%; Age 35–37, 35.5%; Age 38–40, 25.3%; Age 41–42, 14.8%;
  Age >42, 6.1%

Figure 49: Are singleton live birth rates improving for all ART patients or only for those in particular age groups?

Figure 49 is a line graph representing singleton live births per transfer for ART cycles using fresh nondonor eggs or embryos, by woman’s age, and by year from 1996 to 2004.

• 1996: Age <35, 19.3%; Age 35–37, 18.3%; Age 38–40, 15.4%; Age 41–42, 9.5%;
  Age >42, 4.6%
• 1997: Age <35, 20.3%; Age 35–37, 19.8%; Age 38–40, 16.2%; Age 41–42, 10.7%;
  Age >42, 5.0%
• 1998: Age <35, 21.5%; Age 35–37, 20.1%; Age 38–40, 16.9%; Age 41–42, 11.4%;
  Age >42, 5.9%
• 1999: Age <35, 22.3%; Age 35–37, 20.8%; Age 38–40, 17.3%; Age 41–42, 11.6%;
  Age >42, 6.3%
• 2000: Age <35, 23.6%; Age 35–37, 21.3%; Age 38–40, 17.7%; Age 41–42, 11.8%;
  Age >42, 5.3%
• 2001: Age <35, 24.8%; Age 35–37, 22.9%; Age 38–40, 18.5%; Age 41–42, 11.9%;
  Age >42, 5.8%
• 2002: Age <35, 26.3%; Age 35–37, 24.0%; Age 38–40, 19.3%; Age 41–42, 11.9%;
  Age >42, 6.2%
• 2003: Age <35, 26.6%; Age 35–37, 24.8%; Age 38–40, 19.3%; Age 41–42, 12.4%;
  Age >42, 5.3%
• 2004: Age <35, 27.3%; Age 35–37, 24.3%; Age 38–40, 19.0%; Age 41–42, 12.3%;
  Age >42, 5.6%

Figure 50: Has the number of embryos transferred in fresh–nondonor cycles changed?

Figure 50 is a bar graph representing the percentage of fresh–nondonor cycles that involved the transfer of one, two, three, or four or more embryos, by year from 1996 to 2004.

• 1996: One, 6%; Two, 10%; Three, 23%; Four or more, 62%
• 1997: One, 6%; Two, 11%; Three, 27%; Four or more, 56%
• 1998: One, 5%; Two, 15%; Three, 33%; Four or more, 46%
• 1999: One, 6%; Two, 23%; Three, 34%; Four or more, 36%
• 2000: One, 6%; Two, 26%; Three, 35%; Four or more, 34%
• 2001: One, 6%; Two, 27%; Three, 35%; Four or more, 32%
• 2002: One, 7%; Two, 32%; Three, 34%; Four or more, 28%
• 2003: One, 7%; Two, 36%; Three, 33%; Four or more, 24%
• 2004: One, 8%; Two, 39%; Three, 32%; Four or more, 21%

Figure 51: Has the number of embryos transferred in each ART cycle changed for women younger than 35 who have more embryos available than they choose to transfer?

Figure 51 is a bar graph representing the percentage of fresh–nondonor cycles that involved the transfer of two, three, or four or more embryos in women who were younger than 35 and set aside extra embryos for future use, by year from 1996 to 2004. Note: Cycles involving the transfer of one embryo were not included because of the small number of cycles where one embryo was transferred and extra embryos were set aside for future use.

• 1996: Two, 3%; Three, 33%; Four or more, 64%
• 1997: Two, 6%; Three, 43%; Four or more, 51%
• 1998: Two, 17%; Three, 50%; Four or more, 33%
• 1999: Two, 36%; Three, 45%; Four or more, 19%
• 2000: Two, 45%; Three, 40%; Four or more, 15%
• 2001: Two, 49%; Three, 39%; Four or more, 12%
• 2002: Two, 56%; Three, 35%; Four or more, 9%
• 2003: Two, 63%; Three, 30%; Four or more, 7%
• 2004: Two, 70%; Three, 25%; Four or more, 5%
   

Figure 52: Have there been improvements in live birth rates, by number of embryos transferred?

Figure 52 is a line graph representing live births per transfer, by number of embryos transferred, and by year from 1996 to 2004.

• 1996: One, 6.2%; Two, 14.4%; Three, 29.3%; Four or more, 31.6%
• 1997: One, 8.1%; Two, 19.6%; Three, 33.6%; Four or more, 32.2%
• 1998: One, 8.0%; Two, 26.1%; Three, 35.8%; Four or more, 31.7%
• 1999: One, 11.5%; Two, 30.9%; Three, 35.4%; Four or more, 31.2%
• 2000: One, 9.8%; Two, 34.8%; Three, 34.9%; Four or more, 29.6%
• 2001: One, 11.3%; Two, 37.2%; Three, 36.7%; Four or more, 30.9%
• 2002: One, 12.8%; Two, 39.5%; Three, 37.7%; Four or more, 31.4%
• 2003: One, 13.2%; Two, 40.2%; Three, 36.9%; Four or more, 30.1%
• 2004: One, 13.7%; Two, 40.0%; Three, 35.4%; Four or more, 28.8%
   

Figure 53: Have live birth rates improved for women younger than 35 who have more embryos available than they choose to transfer?

Figure 53 is a line graph representing live births per transfer in women who were younger than 35 and set aside extra embryos for future use, by number of embryos transferred, and by year from 1996 to 2004. Note: Cycles involving the transfer of one embryo were not included because of the small number of cycles where one embryo was transferred and extra embryos were set aside for future use.

• 1996: Two, 38.2%; Three, 41.4%; Four or more, 39.5%
• 1997: Two, 41.6%; Three, 44.8%; Four or more, 40.8%
• 1998: Two, 46.4%; Three, 47.0%; Four or more, 42.0%
• 1999: Two, 46.5%; Three, 47.3%; Four or more, 41.4%
• 2000: Two, 49.8%; Three, 44.8%; Four or more, 39.1%
• 2001: Two, 51.7%; Three, 46.9%; Four or more, 42.9%
• 2002: Two, 51.8%; Three, 49.5%; Four or more, 45.5%
• 2003: Two, 53.3%; Three, 49.2%; Four or more, 46.5%
• 2004: Two, 52.7%; Three, 49.8%; Four or more, 46.8%

Figure 54: Have multiple-infant birth rates changed?

Figure 54 is a line graph representing multiple-infant births per live-birth delivery, by type of ART cycle, and by year from 1996 to 2004.

• 1996: Fresh–nondonor 38.4%, Frozen–nondonor 27.0%, Fresh–donor 41.6%,
  Frozen–donor 26.2%
• 1997: Fresh–nondonor 38.8%, Frozen–nondonor 25.5%, Fresh–donor 44.5%,
  Frozen–donor 34.2%
• 1998: Fresh–nondonor 38.2%, Frozen–nondonor 27.1%, Fresh–donor 43.9%,
  Frozen–donor 27.9%
• 1999: Fresh–nondonor 37.0%, Frozen–nondonor 27.1%, Fresh–donor 41.8%,
  Frozen–donor 30.4%
• 2000: Fresh–nondonor 35.3%, Frozen–nondonor 25.8%, Fresh–donor 40.6%,
  Frozen–donor 29.1%
• 2001: Fresh–nondonor 35.8%, Frozen–nondonor 26.8%, Fresh–donor 41.7%,
  Frozen–donor 28.4%
• 2002: Fresh–nondonor 35.4%, Frozen–nondonor 24.6%, Fresh–donor 42.4%,
  Frozen–donor 27.3%
• 2003: Fresh–nondonor 34.2%, Frozen–nondonor 25.3%, Fresh–donor 40.3%,
  Frozen–donor 26.0%
• 2004: Fresh–nondonor 32.5%, Frozen–nondonor 24.2%, Fresh–donor 40.0%,
  Frozen–donor 26.2%

Figure 55: Have multiple-infant birth rates for cycles using fresh nondonor eggs or embryos changed for all ART patients or only for those in particular age groups?

Figure 55 is a line graph representing multiple-infant births per live-birth delivery, for fresh–nondonor cycles, by woman’s age, and by year from 1996 to 2004.

• 1996: Age <35, 42.6%; Age 35–37, 37.0%; Age 38–40, 28.6%; Age 41–42, 18.0%; Age >42, 14.3%
• 1997: Age <35, 43.6%; Age 35–37, 37.0%; Age 38–40, 28.3%; Age 41–42, 19.3%; Age >42, 18.0%
• 1998: Age <35, 42.4%; Age 35–37, 37.0%; Age 38–40, 28.4%; Age 41–42, 19.7%; Age >42, 15.0%
• 1999: Age <35, 41.1%; Age 35–37, 35.8%; Age 38–40, 28.5%; Age 41–42, 14.5%; Age >42, 12.2%
• 2000: Age <35, 38.6%; Age 35–37, 35.3%; Age 38–40, 27.2%; Age 41–42, 17.6%; Age >42, 12.2%
• 2001: Age <35, 39.7%; Age 35–37, 34.7%; Age 38–40, 27.2%; Age 41–42, 17.9%; Age >42, 14.4%
• 2002: Age <35, 38.9%; Age 35–37, 35.4%; Age 38–40, 26.9%; Age 41–42, 18.6%; Age >42, 6.5%
• 2003: Age <35, 38.4%; Age 35–37, 32.1%; Age 38–40, 26.1%; Age 41–42, 17.4%; Age >42, 10.2%
• 2004: Age <35, 36.1%; Age 35–37, 31.5%; Age 38–40, 24.9%; Age 41–42, 16.8%; Age >42, 8.2%

Figure 56: Have the percentages of singletons, twins, and triplets or more changed for ART cycles using fresh nondonor eggs or embryos?

Figure 56 is a bar graph representing live births per transfer and percentages of multiple-infant births for ART cycles using fresh nondonor eggs or embryos, by year from 1996 to 2004.

• 1996: Live births per transfer, 28%. Of these live births, 62% were singletons, 31%
  were twins, and 7% were triplets or more.
• 1997: Live births per transfer, 30%. Of these live births, 61% were singletons, 32%
  were twins, and 7% were triplets or more.
• 1998: Live births per transfer, 31%. Of these live births, 62% were singletons, 32%
  were twins, and 6% were triplets or more.
• 1999: Live births per transfer, 31%. Of these live births, 63% were singletons, 32%
  were twins, and 5% were triplets or more.
• 2000: Live births per transfer, 32%. Of these live births, 65% were singletons, 31%
  were twins, and 4% were triplets or more.
• 2001: Live births per transfer, 33%. Of these live births, 64% were singletons, 32%
  were twins, and 4% were triplets or more.
• 2002: Live births per transfer, 35%. Of these live births, 65% were singletons, 32%
  were twins, and 4% were triplets or more.
• 2003: Live births per transfer, 35%. Of these live births, 66% were singletons, 31%
  were twins, and 3% were triplets or more.
• 2004: Live births per transfer, 34%. Of these live births, 67% were singletons, 30%
  were twins, and 3% were triplets or more.

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