2009
2008
- Science’s Breakthrough of the Year: Reprogramming Cells

December 19, 2008
By inserting genes that turn back a cell's developmental clock, researchers are gaining insights into disease and the biology of how a cell decides its fate.
- Cells’ Protein-Folding ‘ER’ May Play a Role in Type 2 Diabetes

November 24, 2008
“It used to be that for a long time, we thought that type 2 diabetes was just your insulin not working – insulin resistance,” says Feroz Papa, MD, PhD.
- Biomedical Engineers’ Detective Work Reveals Antibiotic Mechanism

November 14, 2008
A series of genetic clues led a team of BU biomedical engineers to uncover exactly how certain antibiotics kill bacteria.
- Nature study demonstrates that bacterial clotting depends on clustering

November 3, 2008
Bacteria shown to cause blood clots.
- Random Event Triggers Cellular Switch

October 20, 2008
A stochastic single-molecule event is enough to switch a bacterial cell from one phenotype to another.
- New prenatal test for Down syndrome less risky than amniocentesis, Stanford/Packard scientists say

October 8, 2008
Pregnant women worried about their babies’ genetic health face a tough decision: get prenatal gene testing and risk miscarriage, or skip the tests and miss the chance to learn of genetic defects before birth.
- Important new step toward producing stem cells for human treatment

September 25, 2008
Harvard researchers produce iPS cells without use of retroviruses.
- New Protein Structure Could Spur Research on Metabolism, Cell Death

September 4, 2008
Researchers have determined the structure of a human membrane protein involved in metabolism and the self-destruction of cells.
- Infections linked to premature births more common than thought, Stanford study finds

August 25, 2008
Previously unrecognized and unidentified infections of amniotic fluid may be a significant cause of premature birth, according to researchers at the Stanford University School of Medicine.
- Amplifying Small Molecules

August 14, 2008
Supramolecular complex generates target compounds in PCR-like cascade reaction.
- Daley and colleagues create 20 disease-specific stem cell lines

August 7, 2008
Lines to be part of new HSCI iPS collection available to researchers.
- Scientists discover the travel patterns of seasonal flu

April 16, 2008
Scientists discover the travel patterns of seasonal flu – findings may lead to improved flu vaccines.
- Scientists Identify New Leads for Treating Parasitic Worm Disease
March 16, 2008
Compounds May Provide Much-Needed New Weapons In Worldwide Battle Against Schistosomiasis.
- Bird brains suggest how vocal learning evolved

March 11, 2008
Though they perch far apart on the avian family tree, birds with the ability to learn songs use similar brain structures to sing their tunes.
- Regulator of microRNAs is key to cell reprogramming and carcinogenesis

February 21, 2008
MicroRNAs are a recently discovered class of RNAs that encode no proteins but instead regulate gene activity.
- DNA is blueprint, contractor and construction worker for new structures

January 31, 2008
DNA is the blueprint of all life, giving instruction and function to organisms ranging from simple one-celled bacteria to complex human beings.
- Team IDs weakness in anthrax bacteria

January 22, 2008
MIT and New York University researchers have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics.
- Study: Brain connections strengthen during waking hours, weaken during sleep

January 20, 2008
Most people know it from experience: After so many hours of being awake, your brain feels unable to absorb any more—and several hours of sleep will refresh it.
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