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adenovirus 5-tumor necrosis factor alpha A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | AdGV11-TNFalpha tumor necrosis factor adenovirus 5 vector | | | US brand name: | | TNFerade | | | Abbreviations: | | Ad 5-TNF Alpha Ad5-TNFa | | |
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