Children were especially vulnerable in the era of the Holocaust. The Nazis advocated killing children of "unwanted" or "dangerous" groups in accordance with their ideological views, either as part of the "racial struggle" or as a measure of preventative security. The Germans and their collaborators killed children both for these ideological reasons and in retaliation for real or alleged partisan attacks.

The Germans and their collaborators killed as many as 1.5 million children, including over a million Jewish children and tens of thousands of Romani (Gypsy) children, German children with physical and mental disabilities living in institutions, Polish children, and children residing in the occupied Soviet Union. The chances for survival for Jewish and some non-Jewish adolescents (13-18 years old) were greater, as they could be deployed at forced labor.