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Other Disorders Related to Bone

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Updated March 2005

Osteoporosis: Peak Bone Mass in Women

Bones are the framework for your body. Bone is living tissue that changes constantly, with bits of old bone being removed and replaced by new bone. You can think of bone as a bank account, where you make "deposits" and "withdrawals" of bone tissue.

During childhood and adolescence, much more bone is deposited than withdrawn, so the skeleton grows in both size and density. Up to 90 percent of peak bone mass is acquired by age 18 in girls and age 20 in boys, which makes youth the best time to "invest" in your bone health.

The amount of bone tissue in the skeleton, known as bone mass, can keep growing until around age 30. At that point, bones have reached their maximum strength and density, known as peak bone mass. In women, there tends to be minimal change in total bone mass between age 30 and menopause. But in the first few years after menopause, most women experience rapid bone loss, a "withdrawal" from the bone bank account, which then slows but continues throughout the postmenopausal years. This loss of bone mass can lead to osteoporosis. Given the knowledge that high peak bone density reduces osteoporosis risk later in life, it makes sense to pay more attention to those factors that affect peak bone mass.

Factors Affecting Peak Bone Mass

Peak bone mass is influenced by a variety of genetic and environmental factors. It has been suggested that genetic factors (those you were born with and cannot change, like your gender and race) may account for up to 75 percent of bone mass, while environmental factors (like your diet and exercise habits) account for the remaining 25 percent.

Gender: Peak bone mass tends to be higher in men than in women. Before puberty, boys and girls acquire bone mass at similar rates. After puberty, however, men tend to acquire greater bone mass than women.

Race: For reasons still not known, African American females tend to achieve higher peak bone mass than Caucasian females. These differences in bone density are seen even during childhood and adolescence.

Hormonal factors: The hormone estrogen has an effect on peak bone mass. For example, women who had their first menstrual cycle at an early age and those who use oral contraceptives - which contain estrogen - often have high bone mineral density. In contrast, young women whose menstrual periods stop due to extremely low body weight or excessive exercise, for example, may lose significant amounts of bone density, which may not be recovered even after their periods return.

Nutrition: Calcium is an essential nutrient for bone health. Calcium deficiencies in young people can account for a 5 to 10 percent difference in peak bone mass and can increase the risk for hip fracture later in life. Surveys indicate that teenage girls in the United States are less likely than teenage boys to get enough calcium. In fact, less than 10 percent of girls ages 9 to 17 are actually getting the calcium they need each day.

Physical Activity: Girls and boys and young adults who exercise regularly generally achieve greater peak bone mass than those who do not. Women and men older than age 30 can help prevent bone loss with regular exercise. The best exercise for your bones is weight-bearing exercise. This is exercise that forces you to work against gravity, such as walking, hiking, jogging, stair climbing, tennis, dancing, and weight lifting.

Lifestyle Behaviors: Smoking has been linked to low bone density in adolescents and is associated with other unhealthy behaviors, such as alcohol use and a sedentary lifestyle. The negative impact that smoking has on peak bone mass is further worsened by the fact that those who begin smoking at a younger age are more likely to be heavier smokers later in life. These older smokers are at further risk for bone loss and fracture.

The impact of alcohol on peak bone mass is not clear. The effects of alcohol on bone have been more extensively studied in adults, and the results indicate that high consumption of alcohol has been linked to low bone density. Experts assume that high consumption of alcohol in youth has a similar adverse effect on skeletal health.

NIH Osteoporosis and Related Bone Diseases ~ National Resource Center

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Email: NIAMSBoneInfo@mail.nih.gov
Website: http://www.niams.nih.gov/Health_Info/bone/default.asp

The NIH Osteoporosis and Related Bone Diseases ~ National Resource Center provides patients, health professionals, and the public with an important link to resources and information on metabolic bone diseases. The mission of NIH ORBD~NRC is to expand awareness and enhance knowledge and understanding of the prevention, early detection, and treatment of these diseases as well as strategies for coping with them.

The NIH Osteoporosis and Related Bone Diseases ~ National Resource Center is supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases with contributions from:

The National Institutes of Health (NIH) is a component of the U.S. Department of Health and Human Services (DHHS).

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