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indium In 111 monoclonal antibody huPAM4
The humanized monoclonal antibody huPAM4, directed against the pancreatic cancer antigen MUC-1 and radiolabled with the gamma-emitting radioisotope indium I 111, with radioisotopic and antibody activities. Upon administration, indium In 111 monoclonal antibody huPAM4 may bind to MUC-1-positive tumor cells, allowing radioimmunolocalization with gamma scintigraphy. Overexpressed by many tumor cell types, MUC-1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | 111 In- labeled humanized PAM4 IgG | | |
| Previous: | indium I 111 chimeric monoclonal antibody G250, indium In 111 chimeric monoclonal antibody 806, indium In 111 CHX-A DTPA trastuzumab, indium In 111 ibritumomab tiuxetan, indium In 111 monoclonal antibody BrE-3 | | Next: | indium In 111 pentetate, indium In 111-CMD-193, indium In 111-labeled autologous peripheral blood mononuclear cells, indium In 111-labeled autologous polymorphonuclear leukocytes, Indocin |
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