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The Biological Biochemical Image Database is supported by the Gene Expression and Genomics Unit, Gerontology Research Center, National Institute on Aging, National Institutes of Health, USA.

This page contains information regarding the rationale, submissions, contributors and documentation, scientific disclaimer, and errors.

Rationale:

The rationale for this collection is that:

Except in a few cases, information on most biological pathways in higher eukaryotes is non-existent, incomplete, or conflicting. Similar biological pathways differ by tissue context, developmental stages, stimulatory events, or for other complex reasons. This database allows comparisons of different variations of pathways that can be tested empirically. The goal of this database is to use images created directly by biomedical scientists who are specialists in a particular biological system. It is specifically designed to NOT use average, idealized or redrawn pathways. It does NOT use pathways defined by computer algorithm or information search approaches. Information on biological pathways in higher eukaryotes generally resides in the images and text of review papers. Much of this information is not easily accessible by current medical reference search engines. All images are attributable to the original authors.

Submissions or Image Suggestions:

Suggestions on review papers that contain images of biological pathways are greatly appreciated. Suggestions of images do not have to be your personal work, just pathways or macromolecular structures that you find interesting. We will get permission from the publisher. NO IMAGES WILL BE USED WITHOUT THE WRITTEN PERMISSION FROM THE PUBLISHER, OR PERMISSION FROM THE CONTRIBUTOR, IF THEY ARE UNPUBLISHED.

Images with detail, gene names, and color, are all of greater value. If you would like, your name will be included in an image contributors and documentation list, with or without contact information. [Return to Top]

NO IMAGES FROM BBID MAY BE USED WITHOUT BOTH THE WRITTEN PERMISSION FROM THE ORIGINAL PUBLISHER AND THE BBID DATABASE ADMISISTRATOR.

Please send scientific comments on biological pathways. If you have information that a given pathway extends in a particular direction or activates particular downstream genes, please contribute this as a comment. We will attach it to a comments list for a particular pathway.

Scientific Disclaimer and Caution:

All pathways or other biological systems described here are graphic representations of natural systems. Each pathway is to be considered a work in progress. Each carries some degree of error or incompleteness. The end user has the ultimate responsibility to determine the scientific correctness and validity in their particular biological system.

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Acknowledgements:

The authors would like to thank:

Meelis Kolmer, Ph.D. National Public Health Institute, Helsinki, Finland Shawnte L. White, Cheyney University, Cheyney, Pennsylvania

Errors:

Please send comments regarding any errors, inconsistencies, or any other issue regarding this database. This will help to curate the collection.

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Send suggestions, comments, image/pathway submissions to:

Kevin G. Becker Ph.D. Gene Expression and Genomics Unit National Institute on Aging, NIH Triad Technology Center, Room 207 333 Cassell Drive Baltimore, MD 21224-6825

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Updated: Thursday October 11, 2007