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NCI Highlights
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Phase of Trial
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1.
Phase II-III HMM vs FAC (5-FU/ADR/CTX) Chemotherapy for Advanced Transitional Cell Bladder Cancer with Impaired Renal Function
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Closed
no age specified
NCI
SWOG-7904
2.
Consolidation Hemi-Body Irradiation plus Chemotherapy with CMFP (CTX/MTX/5-FU/PRED) or CAF (CTX/ADR/5-FU) for Metastatic Breast Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Closed
70 and under
NCI
EST-PE-179
Last Modified:
8/10/2007
3.
Phase III Master Protocol for Randomized Comparison of Single-agent Chemotherapy vs Standard Therapy with CAF (CTX/DOX/5-FU) in Previously Untreated Patients with Stage IV Breast Carcinoma --- Amonafide and Other Phase II Agents
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Completed
16 to physiologic 70
NCI
CLB-8642
CALGB-8642
4.
Phase II/III Randomized Comparison of CAF (CTX/ADR/5-FU) vs Palliative Radiotherapy Alone in Patients with Hormone-Refractory Prostate Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Closed
over 18
MRH-860408
NCI-V86-0099
Last Modified:
1/1/1998
5.
Phase II Study of Multimodality Therapy for Women with Locally Advanced Breast Cancer: Neoadjuvant Cyclophosphamide/Doxorubicin/Fluorouracil (CAF) Followed by Radiotherapy with Mitomycin Followed by Surgery Followed by Adjuvant CAF or Mitoxantrone/Fluorouracil/Leucovorin (Summary Last Modified 01/98)
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Closed
20 to 65
Other
YALE-HIC-7996
NCI-V95-0728
Last Modified:
12/28/2006
6.
Phase III Randomized Study of Neoadjuvant Fluorouracil, Doxorubicin, and Cyclophosphamide (FAC) Versus Cyclophosphamide, Methotrexate, and Fluorouracil (CMF) in Women With Stage III Breast Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Temporarily closed
21 to 75
Other
GOCS-08-BR-95-III
NCI-F95-0036, NCT00002696
Last Modified:
3/1/2000
7.
Phase IIIB Randomized Study of Doxorubicin plus the Cardioprotectant Dexrazoxane vs Observation in Women with Advanced Breast Cancer That is Stable or Responding After 6 Courses of First-Line Cyclophosphamide/Doxorubicin/Fluorouracil (CAF) (Summary Last Modified 03/2000)
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Supportive care, Treatment
Closed
18 and over
Pharmaceutical / Industry
PHARMACIA-088050
NCI-V96-0828
Last Modified:
9/1/1997
8.
Phase III Randomized Study of High Dose Chemotherapy,Autologous Bone Marrow Transplantation, and Peripheral Blood Stem Cell Autographs, for Patients with High Risk Primary Breast Cancer (Summary Last Modified 09/97)
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Closed
Under 65
NCI
MDA-DM-89102
NCI-G96-1012
9.
Phase III Study of Major Hormonal Ablation with or without CAF Chemotherapy for ER Positive Metastatic Breast Carcinoma
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Closed
under 70
SEG-78BRE0103
SEG-78BRE336
10.
Phase III Medical Adrenalectomy with Aminoglutethimide and HC with or without CAF (CTX/ADR/5-FU) for ER-Positive Metastatic Breast Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Closed
70 and under
SEG-80BRE370
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