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Re-186 hydroxyethylidene diphosphonate An synthetic compound containing the organic phosphonate hydroxyethylidene diphosphonate (HEDP) labeled with the radioisotope rhenium Re 186. Re-186 hydroxyethylidene diphosphonate binds to hydroxyapatitie in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. Re-186 is a beta emitter with a short half-life, a radioisotope profile that provides localized antitumor radiocytotoxicity while sparing extramedullary bone marrow tissues. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090115044403im_/http://www.cancer.gov/images/spacer.gif) | 186Re-etidronate Re 186 hydroxyethylidene diphosphonate rhenium Re 186 etidronate rhenium Re 186 etidronate Rhenium-186 HEDP rhenium-186 hydroxyethylidene diphosphonate | | ![](https://webarchive.library.unt.edu/eot2008/20090115044403im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20090115044403im_/http://www.cancer.gov/images/spacer.gif) | Re-186 HEDP rhenium-186 HEDP | | ![](https://webarchive.library.unt.edu/eot2008/20090115044403im_/http://www.cancer.gov/images/spacer.gif) |
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