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Guide to the Application of Genotyping to Tuberculosis Prevention and ControlReturn to Genotyping Main MenuTuberculosis Genotyping Case Studies: How TB Programs Have Used GenotypingUsing Genotyping to Evaluate the Impact of a Screening ProgramThe staff of Denver Metro TB Clinic, Denver Public Health Department used genotyping results to evaluate their skin test and symptom screening program among the homeless (Kong 2002). Previous genotyping results had demonstrated an association between recent TB transmission and homelessness. In response, the Clinic developed a screening program for homeless persons, which required annual TSTs and chest radiography for tuberculin reactors or those with symptoms of tuberculosis. This intervention boosted estimated skin-testing coverage from 27% to 67% among the homeless from 1995 through 1998. Latent TB infection treatment completion increased minimally from 19% to 37% in the same time period. The Clinic’s screening program was associated with a decrease in the TB rate from 510 per 100,000 homeless persons in 1995 to 121 in 1998. The estimated proportion of TB cases resulting from recent transmission within the homeless population, defined as cases that were clustered within the previous 2 years, decreased from 49% (1988–1994) to 14% (1995–1998). Last Reviewed: 05/18/2008 |
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If you would like to order any of the DTBE publications please visit the online order form. You will need Adobe Acrobat™ Reader v5.0 or higher to read pages that are in PDF format. Download the Adobe Acrobat™ Reader. If you have difficulty accessing any material on the DTBE Web site because of a disability, please contact us in writing or via telephone and we will work with you to make the information available. Division of Tuberculosis Elimination
Centers for Disease Control & Prevention |