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Meet Elizabeth (Libby) H. Howze

Dr. Elizabeth Howze PictureElizabeth (Libby) H. Howze, ScD, CHES, is the new Director of the Division of Toxicology and Environmental Medicine at ATSDR in Atlanta, Georgia. Dr. Howze worked in family planning in the Peace Corps in Sri Lanka during 1967-1969. She graduated from the Johns Hopkins University School of Hygiene and Public Health in 1985 with a doctorate in public health education.

Dr. Howze moved to Atlanta in 1994 to serve as Chief of the Health Interventions and Translation Branch in the National Center for Chronic Disease Prevention and Health Promotion at the Centers for Disease Control and Prevention (CDC). Her branch was instrumental in helping redirect public health research and practice in nutrition and physical activity from a focus on individual behavior change to a public health ecologic framework that emphasized policy and environmental change. As branch chief—and later as the Associate Director for Health Promotion in the Division of Nutrition and Physical Activity at CDC—she provided leadership in the development, release, and dissemination of the first Surgeon General's report on physical activity and health. Dr. Howze also directed the nutrition and physical activity communications team, one of the first social marketing initiatives at CDC.

About her work as a division director at ATSDR, Dr. Howze says, "I've spent most of my public health career working on the prevention and control of chronic diseases. Coming to work in environmental health promotion at ATSDR presents a whole new set of challenges for me. First, how can we most effectively assist communities that have been impacted by hazardous chemicals? And second, what public health actions can be taken to prevent similar harm from occurring to other communities? The growing science base linking environmental exposures to chronic diseases makes the work that ATSDR does all the more important. I'm excited to be part of it."

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Childhood Lead Poisoning in Missouri and Kansas

Lead poisoning in children remains a problem in many areas with older homes and poor families. ATSDR has conducted screening programs to detect lead poisoning in children and provided funds for its state public health partners to develop community screening programs.

A Closer Look

Initial lead exposure studies in Jasper County, Missouri (1), and Galena, Kansas (2), led to follow-up health studies to determine whether blood lead levels in children decreased in response to soil remediation and a health education campaign for the community and health professionals. ATSDR funded follow-up health studies for these areas through an interagency agreement with the U.S. Environmental Protection Agency (EPA).

Missouri Department of Health and Senior Services, Oronogo-Duenweg Mining Belt Site, Jasper County, Missouri

Tri-State MapThe Oronogo-Duenweg Mining Belt site is in Jasper County in southwestern Missouri. The site is part of the Tri-State Mining District, which covers an area of approximately 2,500 square miles in southwestern Missouri, southeastern Kansas, and northeastern Oklahoma. Mining, milling, and smelting of lead and zinc ore began in 1850 and continued in the district until the 1970s.

In 1991, the Missouri Department of Health and Senior Services conducted a health study of people exposed to lead and cadmium and living in areas affected by past mining activities at the Jasper County Superfund site (1). The study, completed in May 1994, indicated that 14% of children aged 6 to 71 months and living in the study area had blood lead levels 10 micrograms per deciliter (µg/dL). The study also showed that the primary cause of elevated blood lead was exposure to lead-contaminated soils.

Subsequently, EPA released a plan to set priorities for and remediate areas with elevated levels of soil lead. The plan called for time-critical removal of surface soil at 294 residences and six day care centers. By June 2000, EPA had remediated 2,288 residential yards; by October 2000, an additional 51 yards had been remediated.

For more information on the Jasper County study, contact

Scott Clardy, Section Chief
Section for Environmental Public Health
Missouri Department of Health and Senior Services
573-751-6404

Kansas Department of Health and Environment, Cherokee County Superfund Site, Galena Subsite, Cherokee County, Kansas

Galena, Kansas, is in the southeast corner of Cherokee County, Kansas. The Galena Superfund site is one of six former smelter subsites in Cherokee County. In the Tri-State area of Kansas, Missouri, and Oklahoma, mining and smelting operations for lead ore recovery began in 1876 and ended in 1979. Mining and smelting for zinc ore recovery began in the 1890s and ended in the 1960s.

In July 1990, the Kansas Department of Health and Environment conducted a human exposure study of lead and urine cadmium in children between 6 months and 6 years of age living near the Galena, Kansas, Mine Tailings Superfund site (2). The study concluded that children younger than 6 years had higher blood lead levels than did a control group of same-aged children. Lead levels in six (10.5%) of 57 children in Galena exceeded the Centers for Disease Control and Prevention lead guideline of 10 µg/dL (3). No children in the control community had elevated blood lead levels (n=128).

Since the initial health study, EPA has completed residential cleanups at 664 properties in Galena, where more than 1,500 properties were tested.

For more information on the Cherokee County study, contact

Maria Albert, Manager,
Pre-Renovation Education Program
Kansas Childhood Lead Poisoning Prevention Program
Kansas Department of Health and Environment
785-368-7389

Follow-Up Studies

Near the end of the soil remediation activities, ATSDR entered into grants with the Missouri Department of Health and Senior Services and Kansas Department of Health and Environment to conduct a follow-up health study in each state. Each study is an EPA initiative and fully funded by EPA. The goal of the follow-up health studies is to

  • evaluate the effects of major interventions in each area (soil remediation plus an extensive community and professional health education campaign) and
  • determine their effectiveness in reducing the mean blood lead levels of all children, thereby reducing the proportion of children with elevated blood lead levels.

Follow-up study activities include

  • collecting blood lead samples from a selected number of children younger than 6 years.
  • collecting and analyzing environmental samples (such as dust, soil, interior paint, and tap water).
  • collecting behavioral, occupational, and socioeconomic data.

Missouri Department of Health and Senior Services study participants included

  • 215 participants from the original study area and
  • 72 participants from an expanded area. Participants were children from 6 months to 6 years of age.

Study activities in Missouri include

  • environmental and biologic sampling (completed),
  • soil exposure questionnaires (completed),
  • statistical analysis of all data, and
  • comparison of follow-up study results with those of the initial study.


The Kansas Department of Health and Environment study included analysis of

  • blood samples from 100 children between 6 months and 6 years of age,
  • parent or guardian responses to questions about behavioral risk factors associated with blood lead levels,
  • dust wipe samples of window sills and floors from three rooms in each of the 72 houses in the expanded study area, and
  • composite soil samples from the general yard areas, play areas, and drip line of each house.

In February 2002, the Missouri Department of Health and Senior Services released a draft final report for public comment. The Kansas Department of Health and Environment will release its draft final report for public comment later in the year.—Scott Clardy; Maria Albert; and Lakeisha Sykes, MPH

References

1. Agency for Toxic Substances and Disease Registry. Jasper County, Missouri, Superfund site lead and cadmium exposure study. Atlanta: US Department of Health and Human Services; 1995.

2. Agency for Toxic Substances and Disease Registry. Lead and cadmium exposure study, Galena, Kansas. Atlanta: US Department of Health and Human Services; 1996.

3. Centers for Disease Control and Prevention. Screening young children for lead poisoning: guidance for state and local public health officials. Atlanta: US Department of Health and Human Services; 1997.

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ATSDR: Public Health Detective

Dr. Robert Amler PictureATSDR had to play detective when it undertook the Camp Lejeune survey on birth outcomes in children who were exposed in the womb to trichloroethylene (TCE) and tetrachloroethylene (PCE). ATSDR’s challenge was to find and survey an estimated 16,500 children who might have been conceived or carried in utero during 1968–1985 at Camp Lejeune in Jacksonville, North Carolina, while their mothers lived in on-base housing at U.S. Marine Corps (USMC) Base Camp Lejeune. Birth certificates were available for 12,493 of these children, but no locating information (such as social security numbers [SSNs]) was listed on the birth certificates.

TCE and PCE contamination was found in the wells used at the on-base housing areas at Camp Lejeune. The sources of these contaminants were improper chemical disposal at an on-base motor pool area and an off-base dry-cleaning business. The contamination was discovered during routine tap water sampling, as required for compliance with the Safe Drinking Water Act. No drinking water standards existed for TCE and PCE until 1991 (see box). Early exposure to these contaminants in drinking water has been associated with hearing loss, delays in speech development, and impaired fetal development.

TCE and PCE are solvents that were used as degreasers and as dry cleaning agents. TCE and PCE levels were 1,400 parts per billion (ppb) and 215 ppb, respectively, at the tap. The maximum contaminant level (MCL) (passed in 1991) for both TCE and PCE is 5 ppb. MCLs are standards used to define levels above which water is unsafe for drinking.

Challenges Faced in This Survey

  • We sought women who conceived or were pregnant when they lived on the base between 17 and 34 years ago (1968–1985), as well as the children of those women.
  • Most of these women or their spouses had already left the USMC, and the women’s last names could now be different.
  • Many of the children are now adults; some of them could now be deceased.
  • Initially, we were unable to use files or databases managed under the Department of Defense (DOD) because of concerns about protection of privacy.

Successes

In medical files at the Camp Lejeune Naval Hospital, we found contact information for almost one-third of the 12,493 children for whom we had birth certificates. Additional information was found by reviewing old birth announcements from files of the local newspaper (the Jacksonville Daily News). In addition, the DOD privacy officer agreed that the USMC could try to match names from the 12,493 birth certificates with the Defense Manpower Data Center (DMDC). A USMC staff person was assigned to find databases within the USMC system that could help ATSDR. If a database was found, USMC personnel searched it for ATSDR to see if it contained current addresses, telephone numbers, or SSN information for those persons who had not yet completed the telephone survey. Only exact matches were released to ATSDR. Much information was obtained through this process, and it has been extremely helpful.

What Has Our Investigation Revealed to Date?

The data collection phase of the survey ended on January 26, 2002; 12,598 surveys were completed. A summary report will be available in fall 2002. The report will give the rates of birth defects and childhood cancers in children who participated in the project. If the rates in children conceived or carried at Camp Lejeune are elevated compared with the national rates for these same conditions, further study will attempt to determine potential factors that might have attributed to these increased rates.—Marie L. Socha, DrPH, MS, MSPH

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The National Children's Study

In 1998, the Developmental Disabilities Work Group of the President’s Task Force on Environmental Health Risks and Safety Risks to Children recommended the commission of a longitudinal cohort study of environmental impacts on children. The purpose of the study is to identify subtle, but important, effects of low-level environmental exposures, as well as other biological and social factors on children’s health. In addition, the study will become a valuable resource to answer other questions of scientific interest.

Under the auspices of the task force, several federal agencies, including ATSDR, the National Institute of Child Health and Human Development, the Environmental Protection Agency, the National Institute of Environmental Health Sciences, and the National Center for Environmental Health of the Centers for Disease Control and Prevention have begun work to plan and implement this proposed study. Planning groups of federal scientists and other experts will define specific study hypotheses, study design, technology applications, and ethical guidelines over the next year. Methodologic development and pilot studies are planned for fiscal year 2001–2003. The study is planned to begin in 2004.

The April 2002 study assembly meeting reports will soon be available on the study site (www.nationalchildrensstudy.gov).Exiting the ATSDR Web Site

For information about related research, refer to the Children’s Environmental Health and Safety Inventory of Research (CHEHSIR) (oaspub.epa.gov/chehsir/chehsir.page).Exiting the ATSDR Web Site CHEHSIR is a public database of research, conducted or funded by the federal government, regarding environmental health and safety risks to children.

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Web Site Resources

Earth Image

Children's Health
Government Resources

www.ahcpr.gov/research/chilres1.htmExiting the ATSDR Web Site
The Agency for Health Care Policy and Research (AHCPR) Research on Children’s Health highlights the key findings of the agency in the area of children’s health.

www.atsdr.cdc.gov/child/ochchildhlth.html
Home page of ATSDR’s Office of Children’s Health.

www.childstats.govExiting the ATSDR Web Site
The Federal Interagency Forum on Child and Family Statistics provides statistics in areas such as children’s health.

www.nlm.nih.gov/medlineplus/childrenshealth.htmlExiting the ATSDR Web Site
Medline Plus Children’s Health home page provides an overview of diseases, prevention, and research.

www.nichd.nih.govExiting the ATSDR Web Site
The National Institute of Child Health and Human Development provides information concerning children’s health.

Nongovernment Resources

www.aap.orgExiting the ATSDR Web Site
Home page of the American Academy of Pediatrics.

www.childrennow.org/links/links-health.htmlExiting the ATSDR Web Site
Children Now features a list of links on children’s health.

www.cfw.tufts.eduExiting the ATSDR Web Site
Tufts University Child and Family Webguide features sections on physical and mental health, typical development, education and learning, and more.

Children’s Health and the Environment
Government Resources

yosemite.epa.gov/ochp/ochpweb.nsf/homepageExiting the ATSDR Web Site
The EPA Office of Children’s Health Protection is a gateway to information about environmental threats to children.

www.epa.gov/iaq/schools/tools4s2.htmlExiting the ATSDR Web Site
Information on EPA’s Indoor Air Quality Tools for Schools Kit.

http://www.health.state.mn.us/divs/eh/children/conf2001/directory.htmExiting the ATSDR Web Site
The Children’s Environmental Health Resource Directory is sponsored by the Minnesota Department of Health, Environmental Health Division.

www.niehs.nih.gov/dert/programs/translat/children/children.htmExiting the ATSDR Web Site
The Centers for Children’s Environmental Health and Disease Prevention Research promote translation of basic research findings into applied intervention and prevention methods.

Nongovernment Resources

www.childenvironment.orgExiting the ATSDR Web Site
The Center for Children’s Health and the Environment evaluates the link between exposure to contaminants and childhood illness.

www.childwatch.uio.noExiting the ATSDR Web Site
The Childwatch International Research Network is involved in research on children’s rights, protection, and well-being.

www.cehn.org/cehn/Aboutceh.htmlExiting the ATSDR Web Site
The Children’s Environmental Health Network is a resource on children’s environmental health.

www.checnet.orgExiting the ATSDR Web Site
The Children’s Health Environmental Coalition educates the public about environmental chemicals that can affect children’s health.

www.isde.org/inches.htmlExiting the ATSDR Web Site
Inches (the International Research and Information Network on Children’s Health, Environment and Safety) promotes the protection of children against environmental hazards.

www.iceh.orgExiting the ATSDR Web Site
The mission of the Institute for Children’s Environmental Health is to mitigate children’s exposure to toxicants. The organization sponsors several initiatives.

www.kidsforsavingearth.orgExiting the ATSDR Web Site
Kids for Saving Earth provides free environmental education curricula for all ages.

www.cehi.orgExiting the ATSDR Web Site
The Children’s Environmental Health Institute is dedicated to improving children’s environmental health through education, research, and policy.

www.cepis.ops-oms.org/enwww/salunino/infonoex.htmlExiting the ATSDR Web Site
Children’s Health and the Environment is a collection of facts on the topic of children’s health and the environment from the World Health Organization.

www.ocefoundation.orgExiting the ATSDR Web Site
The mission of Our Children’s Earth Foundation is to protect children through the enforcement of the Clean Air Act.

www.partnersforchildren.orgExiting the ATSDR Web Site
The Partnership for Children’s Health and the Environment is an international coalition of entities whose mission is to protect children from harmful environmental exposures.

www.psr.org/home.cfm?id=childrens_healthExiting the ATSDR Web Site
The Physicians for Social Responsibility home page on children’s environmental health. This organization represents 20,000 physicians, nurses, and other health care professionals who are concerned about environmental health and other issues.

www.preventingharm.orgExiting the ATSDR Web Site
Preventing Harm is a nonprofit organization and resource center focusing on children’s environmental health.

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Recent Publications

Following is information on two recent children’s environmental health publications.

Cover of the BookCreating Safe Learning Zones:
Invisible Threats, Visible Actions

Child Proofing Our Communities Campaign, c/o Center for Health, Environment and Justice, PO Box 6806, Falls Church, VA 22040 (telephone: 703-237-2249; Web: www.childproofing.org;Exiting the ATSDR Web Site e-mail: childproofing@chej.org).

This publication is a followup to the March 2001 Child Proofing Our Communities Campaign publication, Poisoned Schools: Invisible Threats, Visible Actions. Creating Safe Learning Zones: Invisible Threats, Visible Actions includes model school siting legislation to help local communities promote laws and policies that protect children’s health. The report also outlines action steps that parents can take to ensure that their children are not sent to schools that pose unnecessary health risks. The report is available at childproofing.org/cslzindex.html.Exiting the ATSDR Web Site

The Creating Safe Learning Zones: The ABCs of Healthy Schools primer was also recently published on the campaign’s Web site (www.childproofing.org).Exiting the ATSDR Web Site

Cover of the BookRaising Healthy Children in a Toxic World:
101 Smart Solutions for Every Family

Phillip J. Landrigan, Herbert L. Needleman, and Mary Landrigan

Paperback, 152pp. ISBN: 087596947X. Published by St. Martin’s Press, Inc., February 2002.

This publication discusses many environmental dangers that parents and their children face and provides strategies for avoiding those dangers. Topics include allergens, asbestos, contaminated water, heavy metals, herbicides, household chemicals, pesticides, phthalates, pressure-treated wood, radon, solvents, and unsafe foods.


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This page last updated on October 24, 2003
Contact Name: Wilma López/ WLópez@cdc.gov



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