Revised PHS 2590 (DHHS Public Health Service Noncompeting Continuation Progress Report) Now Available

Notice Number: NOT-OD-08-030

Key Dates
Release Date: January 4, 2008

Issued by
National Institutes of Health (NIH), (

EFFECTIVE DATE: The newly revised “Continuation Progress Report for a DHHS Public Health Service Grant” (PHS 2590, rev. 11/07) instructions and forms are now available and will be accepted immediately. All progress reports received on or after March 1, 2008 must use the new instructions and forms. During the transition period the previous version (interim revision 04/2006) will continue to be available, and progress reports using the previous version will be accepted through February 29, 2008. 

The newly revised instructions and forms are available at The forms available on the website continue to be provided in two formats—MS Word and PDF-fillable using Adobe Acrobat Reader Software. Free Adobe Software may be accessed at Applicants are strongly encouraged to access the instructions and forms via the Internet because they provide valuable links to current policy documents and allow easy navigation of the instructions. For further information, contact

Please read the instructions carefully.  This edition of the PHS 2590 implements a number of important policy changes, including NIH Policy for Sharing of Data Obtained in NIH-Supported or Conducted Genome-Wide Association Studies, and registration of clinical trials in as required by Public Law 110-85. 

One significant change to the PHS 2590 is the business process for submission of the continuation progress report.  As of March 1, 2008, only the signed original continuation progress report is required to be submitted to the centralized mailing address (No additional copies required).
The additional changes are highlighted below.

Notable Changes to the PHS 2590 Instructions (rev. 11/07):

Implementation of Grants.Gov Terminology

As part of the ongoing effort to keep the PHS 2590, 398 and the SF424 (R&R) synchronized, new terminology is implemented in the PHS2590:



Non-Competing Continuation Progress Report

Continuation Progress Report

Competing/Administrative Supplement

Revision application

Principal Investigator

Program Director/Principal Investigator (PD/PI)

Key Personnel

Senior/key Personnel

Performance site

Project/performance site

Duly authorized representative

Authorized Organizational Representative

Instruction modifications

Instructions for Career Development Award Applications

Institutional Research Training Application Including Ruth L. Kirschstein-NRSA Applications

Registration Reminders

Progress Report Narrative for T’s and K’s

Changes of note to specific form and format pages:

Face Page

Project/Performance Site Format Page

Checklist Page (Form Page 6)


Inquires about preparing a specific progress report should be directed to the program official and/or grants management specialist of the awarding institute or center.

Inquiries on any changes to the forms and instructions may be directed to:

Grants Info
Office of Extramural Research
National Institutes of Health
Telephone: 301-435-0714
TTY: 301-451-5936

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

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