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eflornithine hydrochloride ointment An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered topically, eflornithine irreversibly inhibits skin ODC activity, thereby inhibiting the synthesis of polyamines; inhibition of polyamine synthesis may result in diminished hair growth and epidermal cell turnover.
Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
![](https://webarchive.library.unt.edu/eot2008/20090115035518im_/http://www.cancer.gov/images/spacer.gif)
Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20090115035518im_/http://www.cancer.gov/images/spacer.gif) | DL-alpha-difluoromethylornitine hydrochloride ointment | | ![](https://webarchive.library.unt.edu/eot2008/20090115035518im_/http://www.cancer.gov/images/spacer.gif) |
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