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Last Modified: 11/1/1988


1.		Phase II/III Randomized Comparison of Two Schedules of TMTX vs 5-FU in Patients with Colorectal Carcinoma (Summary Last Modified 11/88)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III, Phase II				Treatment				Closed				18 and over				NCI				SWOG-8611

Last Modified: 10/22/2007


2.		Phase I/II Chemotherapy with Trimetrexate in Children with Solid Tumors

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II, Phase I				Treatment				Closed				21 and under				NCI				POG-8591

Last Modified: 9/1/1988


3.		Phase I/II Pilot Study of Chemotherapy with CDDP/TMTX or TMTX/VP-16 in Patients with non-Small Cell Lung Cancer (Summary Last Modified 09/88)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II, Phase I				Treatment				Closed				18 to 80								YALE-HIC-4467 NCI-V88-0377

Last Modified: 7/1/1997


4.		Phase II Study of TMTX/5-FU/CF in Recurrent or Refractory Metastatic Urothelial Tract Cancer (Summary Last Modified 07/97)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Completed				over 18				Other				MSKCC-93150 NCI-V94-0477

Last Modified: 5/1/1997


5.		Phase II Study of TMTX/5-FU/CF for Previously Untreated, Unresectable or Metastatic Gastric Cancer (Summary Last Modified 05/97)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Completed				18 and over				Pharmaceutical / Industry				USB-TMTX-B018 UPCC-1294, NCI-V94-0528

Last Modified: 8/10/2006


6.		Phase II Study of Trimetrexate Glucuronate With Leucovorin Calcium Rescue in Children With Recurrent Acute Lymphoblastic Leukemia, Recurrent Osteogenic Sarcoma, or Refractory Non-Hodgkin's Lymphoma Resistant to Methotrexate

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Closed				21 and under at diagnosis				Other				MSKCC-95093 NCI-V96-0840, NCT00002738

Last Modified: 10/1/2002


7.		Phase II Study of Trimetrexate for Advanced, Persistent, or Recurrent Mixed Mesodermal Tumors of the Uterus

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Completed				18 and over				NCI				GOG-130C

Last Modified: 8/15/2006


8.		Phase II Study of Trimetrexate in Refractory Leiomyosarcoma of the Uterus

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Completed				18 and over				NCI				GOG-131D

Last Modified: 12/1/1998


9.		Phase II Study of Trimetrexate, Fluorouracil, and Leucovorin in Unresectable or Metastatic Adenocarcinoma of the Stomach (Summary Last Modified 12/98)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Closed				18 and over				NCI				SWOG-9511

Last Modified: 4/20/2007


10.		Phase II Study of 5-Fluorouracil Modulation with Trimetrexate and Leucovorin in Advanced Pancreatic Cancer (Summary Last Modified 06/2000)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Closed				18 and over				NCI				LAC-USC-3P951 NCI-G97-1173, NCT00002955

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