Diaz, M., and Flajnik, M.F., 1998. Evolution of somatic hypermutation and gene conversion in adaptive immunity. Immunol. Rev. 162: 13-24.
[Abstract]Link_URL http://www.ncbi.nlm.nih.gov/pubmed/9602348?dopt=Abstract
Diaz, M., Greenberg, A.S., and Flajnik, M.F., 1998. Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: Possible role in antigen-driven reactions in the absence of germinal centers. Proc. Natl. Acad. Sci. USA 95: 14343-14348.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/9826702?dopt=Abstract
Diaz, M., Velez, J., Singh, M., Cerny, J., and Flajnik, M.F., 1999. Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: the translesion synthesis model of somatic hypermutation. Internat. Immunol. 11: 825-833.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/10330287?dopt=Abstract
Diaz, M., and Klinman, N.R., 2000. Relative roles of somatic and Darwinian evolution in shaping the antibody response. Immunol. Res. 3: 89-102.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/10852106?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz M., Flajnik M.F., and Klinman, N.R., 2001. Evolution and the molecular basis of somatic hypermutation of antigen receptor genes. Phil. Trans. Roy. Soc. Lond. B 356: 67-72.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/11205333?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Rumfelt, L.L., Avila, D., Diaz, M., Bartl, S., McKinney, E.C., and Flajnik, M., 2001. A shark antibody heavy chain encoded by a non-somatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG. Proc. Natl. Acad. Sci. USA 98: 1775-1780.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/11172027?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Zan, H., Komori A., Li, Z., Cerutti, A., Schaffer, A., Flajnik, M.F., Diaz, M., and Casali, P., 2001. The translesion DNA polymerase z plays a major role in Ig and bcl-6 somatic hypermutation. Immunity 14: 643-653.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/16222339?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz, M., Verkoczy, L., Flajnik, M., and Klinman, N.F., 2001. Decreased frequency of somatic hypermutation and impaired affinity maturation, but intact germinal center formation in mice expressing antisense RNA to DNA polymerase z. J. Immunol. 167: 327-335.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/14517346?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz, M., and Casali, P., 2002. Somatic immunoglobulin hypermutation. Curr.
Opinion Immunol. 14: 235-240.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/11869898?dopt=Abstract
Diaz, M., Stanfield, R.L., Greenberg, A.S., and Flajnik, M.F., 2002. Structural analysis, selection, and ontogeny of the shark new antigen receptor (IgNAR): Identification of a new locus preferentially expressed in early development. Immunogenetics, 54:501-12. [Abstract] http://www.ncbi.nlm.nih.gov/pubmed/12389098?ordinalpos=49&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Kunkel TA, Diaz M. 2002. Enzymatic cytosine deamination: friend and foe. Mol Cell. 10:962-3.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/12453402?ordinalpos=86&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz, M., and Storb, U. 2003. A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes. DNA Repair, 2: 623-627.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/12713818?ordinalpos=17&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz, M., and Verkoczy, L., 2003. Evolution of somatic hypermutation of antigen receptor genes. Encyclopedia of the Human Genome. Nature Publishing Group.
Bartl, S., Baish, M., Weissman, I. L., and M. Diaz. 2002. Did the molecules of adaptive immunity evolve from the innate immune system? Integrative and Comparative Biology 43: 338–346.
Diaz, M., Ray, M., Wheeler, LJ., Verkoczy, L.K., and Mathews, C.K. 2003. Mutagenesis by AID, a molecule critical to immunoglobulin hypermutation, is not caused by an alteration of the precursor nucleotide pool. Mol Immunol. 40:261-268.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/12943798?ordinalpos=78&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz, M., Watson, N.B., Turkington, G., Verkoczy, L.K., Klinman, N.R., and McGregor, W. 2003. Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta. Mol Cancer Res. 1:836-847.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/14517346?ordinalpos=188&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Rogozin IB, Diaz M. 2004. Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process. J Immunol. 172:3382-3384.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/15004135?ordinalpos=53&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Rumfelt LL, Diaz M, Lohr RL, Mochon E, Flajnik MF.2004. Unprecedented multiplicity of Ig transmembrane and secretory mRNA forms in the cartilaginous fish. J Immunol. 173:1129-39.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/15240702?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Brar S, Watson M, Diaz M. 2004. Activation-induced cytosine deaminase, AID, is actively exported out of the nucleus but retained by the induction of DNA breaks. J Biol Chem. 279:26395-401.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/15087440?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Diaz M, Lawrence C. 2005. An update on the role of translesion synthesis DNA polymerases in Ig hypermutation. Trends Immunol. 26:215-20.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/15797512?ordinalpos=43&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Xiao, Z., & Diaz, M. 2005. In Trends in Immunology Research, Chapter 7: Somatic Immunoglobulin Hypermutation in the Memory B Cell Response, editor: Veskler, B. A. (Nova Science, Hauppauge NY) pp 135-146.
Xiao Z., Ray M., Jiang C., Clark A.B., Rogozin I.B., Diaz M. 2007. Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias. Mol Immunol. 44:2659-66.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/17240451?ordinalpos=22&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Brar S.S., Sacho E., Tessmer I., Croteau D.L., Erie D., and Diaz M. 2007. Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. DNA Repair (Amst). 2008 Jan 1;7(1):77-87.
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/17889624?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Jiang C., Foley J., Clayton N., Joniken M., Herbert R., and Diaz M. 2007. Abrogation of lupus nephritis in activation induced deaminase (AID)-deficient MRL/lpr Mice. J Immunol 178:7422-7431
[Abstract] http://www.ncbi.nlm.nih.gov/pubmed/17513793?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Jiang C., Zhao, M.L., and Diaz M. 2009. Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis. Immunology. 126(1):102-113.
[Abstract]Link_URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18624728
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