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ziconotide
A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Prialt | | | | Code name: | | SNX-111 | | |
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