New Mexico

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University of New Mexico

University of New Mexico

General Clinical Research Center
University Hospital, 5E
University of New Mexico Health Sciences Center
2211 Lomas Boulevard Northeast
Albuquerque, NM 87106
http://hsc.unm.edu/som/gcrc/

Grant No. M01 RR00997

Special Assays, Services, or Tests

ACTH
Albumin
Alcohol (ethanol)
Aldosterone
Antidiuretic hormone
Apolipoprotein A-I
Apolipoprotein B
Beta-endorphin
C-peptide
Cortisol–serum and urine
Cotinine–saliva and urine
D-[5]- and D-[4]-tyrosine—GC/MS
11-Deoxycortisol
N,N-dimethyltryptamine
Free fatty acid
FSH
GH

Glucagon
Glucose, D-[2]-glucose, GC/MS
Glycerol, D-[5]-glycerol, GC/MS
Glycohemoglobin
Insulin, polyethylene glycol (PEG) insulin
Ketoacids, GC/MS
Ketones, enzymatic method, GC/MS
Lactate, GC/MS
Leucine, GC/MS
LH
Lipoprotein (a)
D-[5]-L-phenylalanine, GC/MS
Prolactin
Pyruvate, GC/MS
Somatomedin C
TSH

Special Resources, Instruments, or Services

Anthropometry
Beta and gamma counters
Bioelectrical impedance analysis
Chemiluminescence instrument
Complete clinical nutrition services
ELISA assay capability
GC/MS
Grass EEG recorder
HPLC

Hydrostatic weighing center with measurement of residual lung volume by helium dilution
Indirect calorimetry
IREX echocardiography, M mode
Quinton treadmill
Sleep study facility, including 4,500 lux full spectrum light
Vitalog

Major Areas of Investigation

Aging: Longitudinal study of aging process; body composition of the elderly; health status of elderly Hispanics.

Endocrinology: Growth hormone action; regulation of FSH, LH, prolactin, estrogen, and testosterone secretion in acquired hypogonadism of aging and in athletes; pituitary-end-organ function in depressed patients; regulation of gene expression of corticotropin-releasing factor.

Immunology: Tumor immunology; pathobiology; effects of aging on the immune system.

Infectious Diseases: Therapies influencing HIV biology; long-term follow-up of hantavirus infection; papillomavirus infection inducing cervical dysplasia.

Metabolism: Insulin delivery systems; counterregulatory hormones in type 1 and 2 diabetes; brittle diabetes; stable isotope studies of glucose production and disposal; glucose clamp investigations; diabetic complications: neuropathy; role of aldose reductase by nuclear magnetic resonance (NMR); brain energy metabolism during hypoglycemia; diabetes prevention program; minimal model in gestational diabetes; Diabetes Prevention Trial, type 1 diabetes.

Neonatology: Pulsed Doppler flow; infections in newborns; bronchopulmonary dysplasia; cerebral hemorrhage in premature infants; adrenal function in newborns; neonatal pulmonary function; growth factors in neonates; high-frequency ventilation, oxygen utilization in newborns; erythropoietin and cytokine use in critically ill infants; NIH Neonatal Network studies.

Nephrology: Hemodynamics of diabetic nephropathy; endothelin-1 and hypertension in end-stage renal disease.

Neurology: Proton NMR spectroscopy of brain in multi-infarct dementia; natural history of multiple sclerosis by NMR; magnetoencephalography applications in stroke.

Nutrition: Obesity; nutrition in the elderly.

Oncology: Application of recombinant marrow-stimulating hormones in high-dose chemotherapy.

Pediatrics: Protein and ketone turnover in critically ill infants and children; pharmacotherapy of acute asthma; mechanical ventilation and hemodynamics.

Psychiatry: Treatment of schizophrenia; informed consents.

Sports Medicine: Investigation of hydration in competitive athletes.

Women and Minority Health: Health in elderly Hispanics; genetics of asthma in Hispanics; hypoglycemia in diabetic Zuni Indians; molecular epidemiology of breast cancer in New Mexico Hispanics; aldose reductase gene expression in Hispanics; stroke incidence among Hispanics and Native Americans; renal disease in Zuni Indians.

Contact Information

For information about this GCRC and how to access its resources, please contact:

Administrative Manager
Selina R. Keryte, B.A.
505-272-2366; Fax: 505-272-0266
E-mail: skeryte@salud.unm.edu

Program Director
Mark R. Burge, M.D.
505-272-4658; Fax: 272-5155
E-mail: mburge@salud.unm.edu

Principal Investigator
Paul Roth, M.D.
505-272-2321; Fax: 505-272-6581
E-mail: proth@salud.unm.edu

Associate Program Director
Mark Schuyler, M.D.
505-272-6027; Fax: 505-272-0266
E-mail: mschuyler@salud.unm.edu

Associate Program Director
Lu-Ann Papile, M.D.
505-272-3967; Fax: 505-272-6845
E-mail: lpapile@unm.edu

Human Protections Specialist
Cheryl Reich R.N., M.S.N., A.O.C.N.
505-272-0802; Fax: 505-272-3134
E-mail: Reich@salud.unm.edu

GCRC Advisory Committee Chairperson
Jeffery Norenberg, Pharm.D.
505-272-8101; Fax: 505-272-6749
E-mail: jnorenberg@unm.edu

Nurse Manager
Lorraine Martinez, R.N.
505-272-2770; Fax: 505-272-0266
E-mail: jkpayne@salud.unm.edu

Nutrition Research Manager
Rosemary Wold, M.S., R.D., L.D.
505-272-5501; Fax: 505-272-0266
E-mail: rwold@salud.unm.edu

Research Coordinator/Outpatient Supervisor
Sandra McClelland, M.S.N., R.N., C.F.N.P.
505-272-0193; Fax: 505-272-0266
E-mail: SMcClelland@salud.unm.edu

Laboratory Manager
Toney Brazfield
505-272-3619; Fax: 505-272-8391
E-mail: tbrazfield@salud.unm.edu

Biostatistician
Clifford Qualls, Ph.D.
505-272-2368; Fax: 505-272-0266
E-mail: cqualls@salud.unm.edu

Computer Systems Manager
Lori Sloane
505-272-2523; Fax: 505-272-0266
E-mail: lori@salud.unm.edu