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ALTBIB - Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing
ALTBIB is a searchable bibliographic collection on alternatives to animal testing. It includes citations from published articles, books, book chapters, and technical reports from 1980 to 2000. Citations were selected manually after searching various National Library of Medicine (NLM) bibliographic databases. The bibliography features citations concerning methods, tests, assays, and procedures that may prove useful in establishing alternatives to the use of intact vertebrates. ALTBIB has not been updated since 2001 because new features were added to PubMed®/MEDLINE® to assist users in searching and retrieving directly from the file. Search strategies for some animal alternatives have been developed and incorporated in the ALTBIB search interface.
Web Access/Searching
ALTBIB is accessible, free of charge, via TOXNET® at: http://toxnet nlm.nih.gov/altbib.html
Users can search ALTBIB (1980 to 2000) by term or by one of these 16 categories:
- General
- Carcinogenesis
- Cytotoxicity
- Dermal Toxicity
- Ecotoxicity
- Genotoxicity and Mutagenesis
- Hepatic and Renal Toxicity
- Immunotoxicity
- Neurotoxicity
- Ocular Toxicity
- Pharmacokinetic and Mechanistic Studies
- Pulmonary Toxicity
- Quantitative Structure Activity Relationships
- Reproductive and Developmental Toxicity
- Tissue and Organ Toxicity
- Miscellaneous
Users can also search PubMed/MEDLINE from the ALTBIB page using the animal alternative search strategy provided. The search strategy can be limited by date, animal alternative (MeSH) or toxicology subset. Search strategies incorporated in the ALTBIB search interface can be seen by clicking on the detail button in the result page. Strategies can be modified or written de novo.
Users can easily link to additional resources on the 3Rs (reduction, refinement, replacement) and animal testing alternatives, as well as other NLM databases.
Further Information
For detailed information about ALTBIB or TOXNET, contact:
National Library of Medicine
Specialized Information Services
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Telephone: (301) 496-1131
FAX: (301) 480-3537
e-mail: tehip@teh.nlm.nih.gov
URL: http://sis.nlm.nih.gov
Customer Service
National Library of Medicine
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Bethesda, MD 20894
Telephone: 1-888-FINDNLM (1-888-346-3656)
e-mail: custserv@nlm.nih.gov
URL: http://www.nlm.nih.gov
A complete list of NLM Fact Sheets is available at:
(alphabetical list) http://www.nlm.nih.gov/pubs/factsheets/factsheets.html
(subject list): http://www.nlm.nih.gov/pubs/factsheets/factsubj.html
FACT SHEETS
Office of Communications and Public Liaison
National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894
Phone: (301) 496-6308
Fax: (301) 496-4450
email: publicinfo@nlm.nih.gov
Last reviewed: 20 February 2008
Last updated: 24 October 2006
First published: 11 October 2006
Metadata| Permanence level: Permanent: Stable Content