| | Research Articles The Malignant Phenotype of Breast Cancer Cells Is Reduced by COX-2 Silencing Ioannis Stasinopoulos, Noriko Mori, and Zaver M Bhujwalla PMCID: PMC2570592 Pathways to Tumorigenesis—Modeling Mutation Acquisition in Stem Cells and Their Progeny Rina Ashkenazi, Sara N Gentry, and Trachette L Jackson PMCID: PMC2570593 Recurrent Overexpression of c-IAP2 in EBV-Associated Nasopharyngeal Carcinomas: Critical Role in Resistance to Toll-like Receptor 3-Mediated Apoptosis Luc Friboulet, Catherine Pioche-Durieu, Sandrine Rodriguez, Alexander Valent, Sylvie Souquère, Hugues Ripoche, Abdelmajid Khabir, Sai Wah Tsao, Jacques Bosq, Kwok Wai Lo, and Pierre Busson PMCID: PMC2570594 Involvement of Epigenetic Mechanisms in the Regulation of Secreted Phospholipase A2 Expressions in Jurkat Leukemia Cells Mario Menschikowski, Albert Hagelgans, Heike Kostka, Graeme Eisenhofer, and Gabriele Siegert PMCID: PMC2570595 The Neurofibromatosis 2 Tumor Suppressor Gene Product, Merlin, Regulates Human Meningioma Cell Growth by Signaling through YAP Katherine Striedinger, Scott R VandenBerg, Gilson S Baia, Michael W McDermott, David H Gutmann, and Anita Lal PMCID: PMC2570596 Tissue-Specific Ablation of Prkar1a Causes Schwannomas by Suppressing Neurofibromatosis Protein Production Georgette N Jones, Chhavy Tep, William H Towns, II, Georgeta Mihai, Ian D Tonks, Graham F Kay, Petra M Schmalbrock, Anat O Stemmer-Rachamimov, Sung Ok Yoon, and Lawrence S Kirschner PMCID: PMC2570597 Chromosomal Instability Is Associated with Higher Expression of Genes Implicated in Epithelial-Mesenchymal Transition, Cancer Invasiveness, and Metastasis and with Lower Expression of Genes Involved in Cell Cycle Checkpoints, DNA Repair, and Chromatin Maintenance Anna V Roschke, Oleg K Glebov, Samir Lababidi, Kristen S Gehlhaus, John N Weinstein, and Ilan R Kirsch PMCID: PMC2570598 p16INK4a Expression and Absence of Activated B-RAF Are Independent Predictors of Chemosensitivity in Melanoma Tumors Stuart J Gallagher, John F Thompson, James Indsto, Lyndee L Scurr, Margaret Lett, Bo-Fu Gao, Ruth Dunleavey, Graham J Mann, Richard F Kefford, and Helen Rizos PMCID: PMC2570599 Mammary Tumors Initiated by Constitutive Cdk2 Activation Contain an Invasive Basal-like Component Patrick E Corsino, Bradley J Davis, Peter H Nörgaard, Nicole N Teoh Parker, Mary Law, William Dunn, and Brian K Law PMCID: PMC2570600 Mutation and Methylation Analysis of the Chromodomain-Helicase-DNA Binding 5 Gene in Ovarian Cancer Kylie L Gorringe, David YH Choong, Louise H Williams, Manasa Ramakrishna, Anita Sridhar, Wen Qiu, Jennifer L Bearfoot, and Ian G Campbell PMCID: PMC2570601 Tumor-Selective Response to Antibody-Mediated Targeting of αvβ3 Integrin in Ovarian Cancer Charles N Landen, Tae-Jin Kim, Yvonne G Lin, William M Merritt, Aparna A Kamat, Liz Y Han, Whitney A Spannuth, Alpa M Nick, Nicholas B Jennnings, Michael S Kinch, David Tice, and Anil K Sood PMCID: PMC2570602 Chemotherapy-Induced Apoptosis in a Transgenic Model of Neuroblastoma Proceeds Through p53 Induction Louis Chesler, David D Goldenberg, Rodney Collins, Matt Grimmer, Grace E Kim, Tarik Tihan, Kim Nguyen, Slava Yakovenko, Katherine K Matthay, and William A Weiss PMCID: PMC2570603 Overexpression of Cell Surface Cytokeratin 8 in Multidrug-Resistant MCF-7/MX Cells Enhances Cell Adhesion to the Extracellular Matrix Fang Liu, Zhong Chen, Jinhong Wang, Xiaofeng Shao, Ziyou Cui, Chunzheng Yang, Zhenping Zhu, and Dongsheng Xiong PMCID: PMC2570604 Golgi Protein GOLM1 Is a Tissue and Urine Biomarker of Prostate Cancer Sooryanarayana Varambally, Bharathi Laxman, Rohit Mehra, Qi Cao, Saravana M Dhanasekaran, Scott A Tomlins, Jill Granger, Adaikkalam Vellaichamy, Arun Sreekumar, Jianjun Yu, Wenjuan Gu, Ronglai Shen, Debashis Ghosh, Lorinda M Wright, Raleigh D Kladney, Rainer Kuefer, Mark A Rubin, Claus J Fimmel, and Arul M Chinnaiyan PMCID: PMC2570605 Hypoxia-Induced Energy Stress Inhibits the mTOR Pathway by Activating an AMPK/REDD1 Signaling Axis in Head and Neck Squamous Cell Carcinoma Abraham Schneider, Rania H Younis, and J Silvio Gutkind PMCID: PMC2570606 PI3K/Akt Pathway Activation Attenuates the Cytotoxic Effect of Methyl Jasmonate Toward Sarcoma Cells Uri Elia and Eliezer Flescher PMCID: PMC2570607 |
