**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: Pepsin
Catalog Numbers:
    S71975, S76874, P53 100, P53 500, P53-100, P53-500, P53100, P53500,
    S80116-1, S801161
Synonyms:
    Pepsin A; Lactated Pepsin; Pepsin Fortior; Lactated Pepsin Elixir;
    Pepsin 3
Company Identification:  Fisher Scientific
                        1 Reagent Lane
                        Fairlawn, NJ  07410
For information, call:  201-796-7100
Emergency Number:       201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887

         **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
|      CAS#      |              Chemical Name           |    %     |  EINECS#  |
|----------------|--------------------------------------|----------|-----------|
|     9001-75-6  |Pepsin A                              |   100    | 232-629-3 |
+----------------+--------------------------------------+----------+-----------+
         Hazard Symbols: XN
         Risk Phrases: 36/37/38 42

                 **** SECTION 3 - HAZARDS IDENTIFICATION ****

                              EMERGENCY OVERVIEW
Appearance:  white to yellow white.
Warning! May cause allergic respiratory reaction. May cause allergic
skin reaction. Sensitizer. May cause eye and skin irritation.
Ingestion may result in an allergic reaction.
Target Organs: None.

Potential Health Effects
    Eye:
         May cause eye irritation.
    Skin:
         May cause skin irritation.
    Ingestion:
         May cause allergic reaction characterized by a rash.
    Inhalation:
         May cause asthmatic attacks due to allergic sensitization of the
         respiratory tract. May cause respiratory tract irritation.
    Chronic:
         No information found.

                   **** SECTION 4 - FIRST AID MEASURES ****

    Eyes:
         Immediately flush eyes with plenty of water for at least 15 minutes,
         occasionally lifting the upper and lower eyelids. Get medical aid
         immediately.
    Skin:
         Flush skin with plenty of soap and water for at least 15 minutes
         while removing contaminated clothing and shoes. Get medical aid if
         irritation develops or persists.
    Ingestion:
         Never give anything by mouth to an unconscious person. Get medical
         aid. Wash mouth out with water.
    Inhalation:
         Get medical aid immediately. Remove from exposure to fresh air
         immediately. If not breathing, give artificial respiration. If
         breathing is difficult, give oxygen.
    Notes to Physician:
         Treat symptomatically and

                 **** SECTION 5 - FIRE FIGHTING MEASURES ****

    General Information:
         As in any fire, wear a self-contained breathing apparatus in
         pressure-demand, MSHA/NIOSH (approved or equivalent), and full
         protective gear. Can burn in a fire, releasing toxic vapors.
    Extinguishing Media:
         In case of fire, use water, dry chemical, chemical foam, or
         alcohol-resistant foam.
    Autoignition Temperature:Not applicable.
    Flash Point:           Not applicable.
    Explosion Limits, lower:Not available.
    Explosion Limits, upper:Not available.
    NFPA Rating:            Not published.

               **** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

    General Information: Use proper personal protective equipment as indicated
                         in Section 8.
    Spills/Leaks:
         Vacuum or sweep up material and place into a suitable disposal
         container. Clean up spills immediately, observing precautions in the
         Protective Equipment section.

                  **** SECTION 7 - HANDLING and STORAGE ****

    Handling:
         Do not get on skin or in eyes. Avoid ingestion and inhalation. Use
         with adequate ventilation. Wash clothing before reuse.
    Storage:
         Store in a cool, dry place. Store in a tightly closed container.

         **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

    Engineering Controls:
         Good general ventilation should be sufficient to control airborne
         levels. Use adequate ventilation to keep airborne concentrations
         low.

                                Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
|   Chemical Name    |        ACGIH      |       NIOSH       |OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| Pepsin A           |none listed        |none listed        |none listed      |
+--------------------+-------------------+-------------------+-----------------+

    OSHA Vacated PELs:
         Pepsin A:
            No OSHA Vacated PELs are listed for this chemical.

    Personal Protective Equipment

                Eyes:
                      Wear appropriate protective eyeglasses or chemical
                      safety goggles as described by OSHA's eye and face
                      protection regulations in 29 CFR 1910.133 or European
                      Standard EN166.
                Skin:
                      Wear appropriate protective gloves to prevent skin
                      exposure.
            Clothing:
                      Wear appropriate protective clothing to prevent skin
                      exposure.
         Respirators:
                      A respiratory protection program that meets OSHA's 29
                      CFR :1910.134 and ANSI Z88.2 requirements or European
                      Standard EN 149 must be followed whenever workplace
                      conditions warrant a respirator's use. Follow the OSHA
                      respirator regulations found in 29CFR 1910.134 or
                      European Standard EN 149. Always use a NIOSH or
                      European Standard EN 149 approved respirator when
                      necessary.

            **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State:             Solid
Appearance:                 white to yellow white
Odor:                       none reported
pH:                         4.6
Vapor Pressure:             Negligible
Vapor Density:              Not available.
Evaporation Rate:           Negligible.
Viscosity:                  Not available.
Boiling Point:              Not available.
Freezing/Melting Point:     Decomposes.
Decomposition Temperature:  Not available.
Solubility in water:        Soluble in water.
Specific Gravity/Density:   Not available.
Molecular Formula:          Not applicable.
Molecular Weight:           0

                **** SECTION 10 - STABILITY AND REACTIVITY ****

    Chemical Stability:
         Stable.
    Conditions to Avoid:
         Incompatible materials.
    Incompatibilities with Other Materials:
         Strong oxidizers, alcohols, tannins, heavy metal salts.
    Hazardous Decomposition Products:
         Nitrogen oxides, carbon monoxide, carbon dioxide.
    Hazardous Polymerization: Not available.

               **** SECTION 11 - TOXICOLOGICAL INFORMATION ****

    RTECS#:
         CAS# 9001-75-6: SC6132000
    LD50/LC50:
         Not available.
    Carcinogenicity:
      Pepsin A -
         Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
    Epidemiology:
         No data available.
    Teratogenicity:
         No data available.
    Reproductive Effects:
         No data available.
    Neurotoxicity:
         No data available.
    Mutagenicity:
         No data available.
    Other Studies:
         No data available.

                 **** SECTION 12 - ECOLOGICAL INFORMATION ****
 
 

                **** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Chemical waste generators must determine whether a discarded chemical
is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in
40 CFR Parts 261.3. Additionally, waste generators must consult state
and local hazardous waste regulations to ensure complete and accurate
classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

                 **** SECTION 14 - TRANSPORT INFORMATION ****

    US DOT
         No information available
    Canadian TDG
         No information available.

                 **** SECTION 15 - REGULATORY INFORMATION ****

US FEDERAL
    TSCA
         CAS# 9001-75-6 is listed on the TSCA inventory.
       Health & Safety Reporting List
         None of the chemicals are on the Health & Safety Reporting List.
       Chemical Test Rules
         None of the chemicals in this product are under a Chemical Test Rule.
       Section 12b
         None of the chemicals are listed under TSCA Section 12b.
       TSCA Significant New Use Rule
         None of the chemicals in this material have a SNUR under TSCA.
    SARA
       Section 302 (RQ)
         None of the chemicals in this material have an RQ.
       Section 302 (TPQ)
         None of the chemicals in this product have a TPQ.
       SARA Codes
         CAS # 9001-75-6: acute.
       Section 313
         No chemicals are reportable under Section 313.
    Clean Air Act:
         This material does not contain any hazardous air pollutants.
         This material does not contain any Class 1 Ozone depletors.
         This material does not contain any Class 2 Ozone depletors.
    Clean Water Act:
         None of the chemicals in this product are listed as Hazardous
         Substances under the CWA.
         None of the chemicals in this product are listed as Priority
         Pollutants under the CWA.
         None of the chemicals in this product are listed as Toxic Pollutants
         under the CWA.
    OSHA:
         None of the chemicals in this product are considered highly hazardous
         by OSHA.
STATE
    Pepsin A is not present on state lists from CA, PA, MN, MA, FL, or
    NJ.
    California No Significant Risk Level:
    None of the chemicals in this product are listed.
European/International Regulations
    European Labeling in Accordance with EC Directives
         Hazard Symbols: XN
         Risk Phrases:
                      R 36/37/38  Irritating to eyes, respiratory system
                      and skin.
                      R 42  May cause sensitization by inhalation.
         Safety Phrases:
                      S 22  Do not breathe dust.
                      S 24  Avoid contact with skin.
                      S 26  In case of contact with eyes, rinse immediately
                      with plenty of water and seek medical advice.
                      S 36/37  Wear suitable protective clothing and
                      gloves.
  WGK (Water Danger/Protection)
         CAS# 9001-75-6: 0
  United Kingdom Occupational Exposure Limits

  Canada
         None of the chemicals in this product are listed on the DSL/NDSL list.
         This product has a WHMIS classification of Not controlled..
         CAS# 9001-75-6 is not listed on Canada's Ingredient Disclosure List.
  Exposure Limits

                 **** SECTION 16 - ADDITIONAL INFORMATION ****

    MSDS Creation Date: 12/12/1997  Revision #1 Date:  8/02/2000

    The information above is believed to be accurate and represents the best
    information currently available to us. However, we make no warranty of
    merchantability or any other warranty, express or implied, with respect to
    such information, and we assume no liability resulting from its use. Users
    should make their own investigations to determine the suitability of the
    information for their particular purposes. In no way shall the company be
    liable for any claims, losses, or damages of any third party or for lost
    profits or any special, indirect, incidental, consequential or exemplary
    damages, howsoever arising, even if the company has been advised of
    the possibility of such damages.