Section 1 - Product and Company Identification
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Product Identification: T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT
Date of MSDS: 05/19/1997 Technical Review Date: 07/03/1997
FSC: 6810 NIIN: 00-936-4996
Submitter: F BT
Status Code: C
MFN: 01
Article: N
Kit Part: N

Manufacturer's Information

Manufacturer's Name: SIGMA CHEMICAL COMPANY
Post Office Box: 14508
Manufacturer's Address1: 3050 SPRUCE ST
Manufacturer's Address2: SAINT LOUIS, MO 63178-5000
Manufacturer's Country: US
General Information Telephone: 314-771-5765/800-325-3010
Emergency Telephone: 314-771-5765/800-325-3010
Emergency Telephone: 314-771-5765/800-325-3010
MSDS Preparer's Name: N/P
Proprietary: N
Reviewed: Y
Published: Y
CAGE: 21076
Special Project Code: N

Item Description

Item Name: TRIS HYDROXYMETHYL AMINOMETHANE,ANALYZED REAGENT
Item Manager:
Specification Number: NK
Type/Grade/Class: NK
Unit of Issue:
Unit of Issue Quantity:
Type of Container:

Preparer Information

Preparer's Name: SIGMA CHEMICAL COMPANY
Preparer's Address1: 3050 SPRUCE ST
Preparer's Address2: ST LOUIS, MO 63178
Preparer's CAGE: 21076
Assigned Individual: N

Contractor Information

Contractor's Name: SIGMA CHEMICAL COMPANY
Contractor's Address1: 3050 SPRUCE ST
Contractor's Address2: ST LOUIS, MO 63178
Contractor's Telephone: 314-771-5765
Contractor's CAGE: 21076

Section 2 - Compositon/Information on Ingredients
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Ingredient Name: 1,3-PROPANEDIOL , 2-AMINO-2-(HYDROXYMETHYL), TROMETHAMINE
Ingredient CAS Number: 77-86-1 Ingredient CAS Code: M
RTECS Number: TY2900000 RTECS Code: M
=WT: =WT Code:
=Volume: =Volume Code:
>WT: >WT Code:
>Volume: >Volume Code:
<WT: <WT Code:
<Volume: <Volume Code:
% Low WT: % Low WT Code:
% High WT: % High WT Code:
% Low Volume: % Low Volume Code:
% High Volume: % High Volume Code:
% Text: N/K
% Enviromental Weight:
Other REC Limits: N/K
OSHA PEL: N/K OSHA PEL Code: M
OSHA STEL: OSHA STEL Code:
ACGIH TLV: N/K ACGIH TLV Code: M
ACGIH STEL: N/P ACGIH STEL Code:
EPA Reporting Quantity:
DOT Reporting Quantity:
Ozone Depleting Chemical: N


Section 3 - Hazards Identification, Including Emergency Overview
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Health Hazards Acute & Chronic: MAY BE HARMFUL BY INHALATION, INGESTION/SKIN ABSORPTION. EYES/SKIN: IRRITATION. INHALATION: IRRITATING TO MUCOUS MEMBRANES & UPPER RESPIRATORY TRACT.

Signs & Symptoms of Overexposure:
IRRITATION.

Medical Conditions Aggravated by Exposure:
N/K

LD50 LC50 Mixture: ORAL LD50(RAT): 5900 MG/KG
Route of Entry Indicators:
Inhalation: YES
Skin: YES
Ingestion: YES
Carcenogenicity Indicators
NTP: NO
IARC: NO
OSHA: NO
Carcinogenicity Explanation: NONE

Section 4 - First Aid Measures
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

First Aid:
EYES/SKIN: FLUSH W/COPIOUS AMOUNTS OF WATER FOR 15 MINS. INHALATION: REMOVE TO FRESH AIR. GIVE CPR/OXYGEN IF NEEDED. INGESTION: WASH OUT MOUTH W/WATER IF CONSCIOUS. OBTAIN MEDICAL ATTENTION IN ALL CAS ES.

Section 5 - Fire Fighting Measures
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Fire Fighting Procedures:
WEAR SCBA & PROTECTIVE CLOTHING.
Unusual Fire or Explosion Hazard:
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
Extinguishing Media:
WATER SPRAY, CO2, DRY CHEMICAL POWDER/APPROPRIATE FOAM.
Flash Point: Flash Point Text: N/K
Autoignition Temperature:
Autoignition Temperature Text: N/A
Lower Limit(s): N/K
Upper Limit(s): N/K

Section 6 - Accidental Release Measures
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Spill Release Procedures:
WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS & HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A BAG & HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA & WASH SITE AFTER MATERIAL PICKUP I S COMPLETE.

Section 7 - Handling and Storage
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Handling and Storage Precautions:

Other Precautions:


Section 8 - Exposure Controls & Personal Protection
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Repiratory Protection:
USE NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:
MECHANICAL EXHAUST REQUIRED.
Protective Gloves:
COMPATIBLE CHEMICAL RESISTANT
Eye Protection: CHEMICAL SAFETY GOGGLES
Other Protective Equipment: SAFETY SHOWER & EYE BATH, PROTECTIVE CLOTHING.
Work Hygenic Practices: REMOVE/LAUNDER CONTAMINATED CLOTHING & SHOES BEFORE REUSE. WASH THOROUGHLY AFTER HANDLING.
Supplemental Health & Safety Information: MELTING POINT: 340.16-342.14F.

Section 9 - Physical & Chemical Properties
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

HCC:
NRC/State License Number:
Net Property Weight for Ammo:
Boiling Point: Boiling Point Text: 426.2-428F
Melting/Freezing Point: Melting/Freezing Text: (SEE SUPP)
Decomposition Point: Decomposition Text: N/K
Vapor Pressure: N/K Vapor Density: N/K
Percent Volatile Organic Content:
Specific Gravity: N/K
Volatile Organic Content Pounds per Gallon:
pH: N/K
Volatile Organic Content Grams per Liter:
Viscosity: N/P
Evaporation Weight and Reference: N/K
Solubility in Water: N/K
Appearance and Odor: WHITE CRYSTALS
Percent Volatiles by Volume: N/K
Corrosion Rate: N/K

Section 10 - Stability & Reactivity Data
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Stability Indicator: YES
Materials to Avoid:
BASES, OXIDIZING AGENTS.
Stability Condition to Avoid:
MOISTURE.
Hazardous Decomposition Products:
THERMAL COMBUSTION: CO, CO2, NITROGEN OXIDES.
Hazardous Polymerization Indicator: NO
Conditions to Avoid Polymerization:
N/K

Section 11 - Toxicological Information
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Toxicological Information:
N/P

Section 12 - Ecological Information
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Ecological Information:
N/P

Section 13 - Disposal Considerations
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Waste Disposal Methods:
DISSOLVE/MIX W/A COMBUSTIBLE SOLVENT & BURN IN A CHEMICAL INCINERATOR EQUIPPED W/AN AFTERBURNER & SCRUBBER, IAW/FEDERAL, STATE & LOCAL REGULATIONS.

Section 14 - MSDS Transport Information
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Transport Information:
N/P

Section 15 - Regulatory Information
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

SARA Title III Information:
N/P
Federal Regulatory Information:
N/P
State Regulatory Information:
N/P

Section 16 - Other Information
T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT

Other Information:
N/P
HAZCOM Label Information
Product Identification: T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT
CAGE: 21076
Assigned Individual: N
Company Name: SIGMA CHEMICAL COMPANY
Company PO Box:
Company Street Address1: 3050 SPRUCE ST
Company Street Address2: ST LOUIS, MO 63178 US
Health Emergency Telephone: 314-771-5765/800-325-3010
Label Required Indicator: Y
Date Label Reviewed: 10/12/1999
Status Code: A
Manufacturer's Label Number:
Date of Label:
Year Procured: N/K
Organization Code: G
Chronic Hazard Indicator: N/P
Eye Protection Indicator: N/P
Skin Protection Indicator: N/P
Respiratory Protection Indicator: N/P
Signal Word: N/P
Health Hazard:
Contact Hazard:
Fire Hazard:
Reactivity Hazard: