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Develop and pilot test a process to collect positive
samples and the establishment of stably transformed cell lines suitable
for use in performance evaluation/quality assurance of human molecular
genetic tests.
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| Type: |
Contract with Duke University School of Medicine
(#200-2000-10050)
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| Goal(s): |
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The aim of this effort was to develop a process for
developing positive control materials for molecular genetic testing.
Lymphocytes were isolated from residual clinical samples. These cells
were stably
transformed and used in a model proficiency testing program. This work
examined the efficacy of preparing transformed cell lines, their stability
over time, institutional review board (IRB) issues, and quality assurance
issues relevant to the overall process.
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| Progress: |
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This project has been completed. Cell lines developed are
available from Coriell Cell Repositories.
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Science-related Links |
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Science-related Literature References |
This page last reviewed: 8/19/2004
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