Past Updates from the Clinician Registry Listserv
Update Sent June 07, 2007
NOTE: This document is provided for historical purposes only and may not provide our most accurate and up-to-date information. The most current Clinician's information can be found on the Clinician Home Page.
The following is a summary of clinical guidance for evaluation and management of persons potentially exposed to XDR TB on two recent transatlantic flights.
If you have any questions on these or other clinical issues, please write to us at coca@cdc.gov.
Introduction
Summary of Post-exposure TB Evaluation & Testing
Evaluation Algorithm for Non-immunocompromised Contacts
Management of Non-immunocompromised Contacts with Positive TST or QFT-G Results
Evaluation Algorithm for Immunocompromised Contacts
Management of Immunocompromised Contacts with Positive TST or QFT-G Results
Notes for Algorithms
Medical Evaluation of XDR TB Contacts
Introduction
Dear Healthcare Professional,
A person with recently diagnosed culture-confirmed, extensively drug-resistant pulmonary tuberculosis (XDR TB) traveled on the following two extended flights (more than 8 hours in duration) in May 2007:
Date Depart Arrive Airline/Flight#
May 12Atlanta, GA (ATL) Paris, France (CDG)Air France #385 / Delta #8517
May 24 Prague, Czech Republic Montreal, CanadaCzech Air #0104
For purposes of this XDR TB contact investigation, all U.S. residents and citizens who were on the flights listed above are to be considered contacts of the XDR TB patient.
If a person identifies themselves as a passenger on one of these flights, we are requesting your assistance to perform TB evaluation and testing, or to refer the passenger to the appropriate state or local TB Control office so TB testing, evaluation and follow-up can be performed.
TB Controller Officers - State: http://www.cdc.gov/tb/xdrtb/pdf/tbcontrol-state.pdf
TB Controller Officers - City: http://www.cdc.gov/tb/xdrtb/pdf/tbcontrol-city.pdf
Specific information must be collected on each passenger as part of this contact investigation.
Please access the XDR TB Contact Investigation Form (PDF) and enter the requested information.
Please keep a copy of this completed form for your records, give a copy to the person tested, and also please contact your State or Local TB Control office.
For any inquiries related to this investigation, please call your State or Local TB Control office:
TB Controller Officers - State: http://www.cdc.gov/tb/xdrtb/pdf/tbcontrol-state.pdf
TB Controller Officers - City: http://www.cdc.gov/tb/xdrtb/pdf/tbcontrol-city.pdf
Below on this update are the latest algorithms for evaluation and management of both non-immunocompromised and immunocompromised contacts of this XDR TB patient.
We greatly appreciate your assistance on this important international XDR TB contact investigation.
Summary of Post-exposure TB Evaluation & Testing
As noted above, for purposes of this XDR TB contact investigation, all U.S. residents and citizens who traveled on either of the flights listed above are to be considered contacts of the XDR TB patient. Among persons who are infected with M. tuberculosis (i.e., latent tuberculosis infection), it can take 8 to 10 weeks following exposure until the tuberculin skin test (TST) result or QuantiFERON®-TB Gold (QFT-G) becomes positive. A second-round of TB evaluation and testing should be done because a negative TST or QFT-G result obtained <8 weeks after exposure may be considered unreliable for excluding latent tuberculosis infection (LTBI). |
Evaluation Algorithm for Non-immunocompromised Contacts
Management of Non-immunocompromised Contacts
with Positive TST or QFT-G Results
Evaluation Algorithm for Immunocompromised Contacts
Management of Immunocompromised Contacts
with Positive TST or QFT-G Results
Notes for Algorithms
Medical Evaluation of XDR TB Contacts
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- Page last updated June 07, 2007
- Content source: CDC Emergency Communication System (ECS), Division of Health Communication and Marketing (DHCM), National Center for Health Marketing (NCHM)
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