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18F-fluoromisonidazole
A radiofluorinated 2-nitroimidazole derivate with hypoxia-specific tracer activity. Misonidazole is reduced under hypoxic conditions and in reduced form covalently binds to macromolecules in hypoxic cells. 18F (fluorine-18) radiofluorination of misonidazole to form 18F-fluoromisonidazole allows radioisotopic imaging of reduced misonidazole bound to macromolecules in hypoxic cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | 18F-misonidazole | | | | Abbreviation: | | 18F-MISO | | |
| Previous: | 123-I-MIP-1072, 123-I-MIP-1095, 131I-TM-601, 18F-FHBG, 18F-fluoromethylcholine | | Next: | 2-methoxyestradiol, 3'-deoxy-3'-[18F]fluorothymidine, 3,4-methylenedioxymethamphetamine, 3-deazauridine, 4'-iodo-4'-deoxydoxorubicin |
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