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Baits containing an insect growth regulator, hexaflumuron, were used in the historic Presbytere and the Creole House of the Cabildo, in the French Quarter of New Orleans, Louisiana, to control infestations of the Formosan subterranean termite, Coptotermes formosanus Shiraki. As with many historic structures in the French Quarter, these two landmarks have sustained chronic infestations by C. formosanus for the last three decades. Baits were applied using both above-ground and in-ground stations between late 1996 and early 1997. Termite activity was monitored using an acoustic emission detector and in-ground monitoring stations. After consuming ≈0.4-1g hexaflumuron during the three to nine month baiting period, the target populations of C. formosanus in these two buildings were eliminated. No dispersal flights were observed in the springs of 1997 and 1998 from these historic buildings.