KOMP:
NIH Knockout Mouse Project
The goal of the NIH-funded Knockout Mouse Project
(KOMP) is to generate a comprehensive resource of null
mutant alleles, with a reporter, using gene targeting
mutagenesis in mouse strain C57BL/6. The construction
of the KOMP mutant collection is being funded in projects
submitted in response to RFA-HG-05-007
and RFA-DA-06-009.
The purpose of the KOMP is to establish a resource repository
to collect and archive the null mutant alleles, primarily
in the form of cryo-preserved embryonic stem (ES) cells,
as well as associated DNA constructs, and cryo-preserved
embryos or live mice created by the KOMP. The successful
KOMP repository should aim to become self supporting
over time.
The NHLBI Program Officer for KOMP is Deborah
Applebaum-Bowden, Ph.D.
NIH
Knockout Mouse Project
KOMP Data Coordination Center
KOMP Repository
June 2006 to March 2011
Knockout
Mouse Project Initiatives
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