More Examples of Major or "Take" Reactions to Smallpox Vaccination
Formation by days 6-8 post-vaccination of a papule, vesicle, ulcer, or crusted central lesion, surrounded by an area of induration signifies a response to vaccination; this event is referred to as a major reaction or a "take," and usually results in a scar.
Source: Smallpox Vaccination and Adverse Events Training Module, Logical Images
- Page last reviewed February 7, 2007
- Page last updated February 21, 2003
- Content source: Division of Bioterrorism Preparedness and Response (DBPR), National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID), Coordinating Center for Infectious Diseases (CCID)
Get email updates
To receive email updates about this page, enter your email address:
Contact Us:
- Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333 - 800-CDC-INFO
(800-232-4636)
TTY: (888) 232-6348
24 Hours/Every Day - cdcinfo@cdc.gov