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fibrin sealant A plasma-derived fibrin biomatrix preparation consisting of two separate solutions that are combined on application. The sealer protein solution contains clottable human fibrinogen and bovine aprotinin, a fibrinolysis inhibitor; the thrombin solution contains human thrombin and calcium chloride. When the solutions are combined, a clot is formed, reproducing the final stages of the coagulation cascade. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090114224524im_/http://www.cancer.gov/images/spacer.gif) | TISSEEL VH | | ![](https://webarchive.library.unt.edu/eot2008/20090114224524im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090114224524im_/http://www.cancer.gov/images/spacer.gif) | Beriplast P | | ![](https://webarchive.library.unt.edu/eot2008/20090114224524im_/http://www.cancer.gov/images/spacer.gif) |
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