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Manufacturer
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| Aquarium Pharmaceuticals, Inc. |
| 50E Hamilton Street |
| Chalfont |
| PA |
| 18914 |
| 215-822-8181 |
| 215-822-1906 |
| 800-847-0659 |
| 2008-01-09 |
| Products by this manufacturer |
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| The following information (Health Effects, Handling/Disposal, and Ingredients) is taken from the product label and/or the Material Safety Data Sheet (MSDS) prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS.
(Complete MSDS for this product)
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Health Effects
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From MSDS
EMERGENCY OVERVIEW
RISK
May cause CANCER. May cause SENSITIZATION by skin contact.
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Ingestion may produce health damage*. Cumulative effects may result following exposure*. May be harmful to the fetus/ embryo*.
May possibly affect fertility*.
*(limited evidence)
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Accidental ingestion of the material may be damaging to the health of the
individual. A metallic taste, nausea, vomiting and burning feeling in the upper stomach region occur after ingestion of copper and its derivatives. The vomitus is usually green/blue and discolors contaminated skin. Acute poisonings from ingestion are rare due to their prompt removal by vomiting. Should vomiting not occur, or is delayed systemic poisoning may occur producing kidney and liver damage, wide-spread capillary damage, and be fatal; death may occur after relapse from an apparent recovery. Anemia may occur in acute poisoning.
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual.
EYE
Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).
SKIN
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.
INHALED
The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. The material is not thought to produce either adverse health effects or irritation of the respiratory tract following inhalation (as classified using animal models). Nevertheless, adverse effects have been produced following exposure of animals by at least one other route and good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.
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From MSDS
Imidazole is structurally related to histamine and has been used as an antagonist to counteract the effects of excess histamine found in certain
induced physiological conditions (it therefore acts as an antihistamine). Imidazoles have been reported to disrupt male fertility through disruption of
testicular function. 2-Methylimidazole decreased luteinizing hormone secretion and tissue interstitial fluid testosterone concentration two hours after
injection into Sprague Dawley rats. Imidazoles bind to cytochrome P450 heme, resulting in inhibition of catalysis. However, 2-substituted imidazoles are considered to be poor inhibitors. Imidazole is probably an inducer of cytochrome P4502E1. In general, inducers of this isozyme stabilize the enzyme by preventing phosporylation of a serine which leads to heme loss. Several drugs containing an imidazole moiety were retained and bound in connective tissue when administered to laboratory animals. The bound material was primarily recovered from elastin (70%) and the collagen. It is postulated that reaction with aldehydes gives an aldol condensation product. Substance accumulation, in the human body, may occur and may cause some concern following repeated or long-term occupational exposure. Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population. There is ample evidence that this material can be regarded as being able to cause cancer in humans based on experiments and other information. There is some evidence that human exposure to the material may result in developmental toxicity. This evidence is based on animal studies where effects have been observed in the absence of marked maternal toxicity, or at around the same dose levels as other toxic effects but which are not secondary non-specific consequences of the other toxic effects. Exposure to the material may cause concerns for human fertility, on the basis that similar materials provide some evidence of impaired fertility in the absence of toxic effects, or evidence of impaired fertility occurring at around the same dose levels as other toxic effects, but which are not a secondary non-specific consequence of other toxic effects.
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From MSDS
No information provided.
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From MSDS
SWALLOWED
- For advice, contact a Poisons Information Center or a doctor at once.
- Urgent hospital treatment is likely to be needed.
- If swallowed do NOT induce vomiting.
- If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration.
- Observe the patient carefully.
- Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious.
- Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink.
- Transport to hospital or doctor without delay.
EYE
If this product comes in contact with the eyes:
- Wash out immediately with fresh running water.
- Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids.
- If pain persists or recurs seek medical attention.
- Removal of contact lenses after an eye injury should only be undertaken by
skilled personnel.
SKIN
If skin contact occurs:
- Immediately remove all contaminated clothing, including footwear
- Flush skin and hair with running water (and soap if available).
- Seek medical attention in event of irritation.
INHALED
- If fumes or combustion products are inhaled remove from contaminated area.
- Other measures are usually unnecessary.
NOTES TO PHYSICIAN
Treat symptomatically.
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| N |
| N |
| N |
0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe;
N = No information provided by manufacturer; * = Chronic Health Hazard |
| 2007-12-11 |
| 2006-01-05 |
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Handling/Disposal
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From MSDS
PROCEDURE FOR HANDLING
- Avoid all personal contact, including inhalation.
- Wear protective clothing when risk of exposure occurs.
- Use in a well-ventilated area.
- Prevent concentration in hollows and sumps.
- DO NOT enter confined spaces until atmosphere has been checked.
- DO NOT allow material to contact humans, exposed food or food utensils.
- Avoid contact with incompatible materials.
- When handling, DO NOT eat, drink or smoke.
- Keep containers securely sealed when not in use.
- Avoid physical damage to containers.
- Always wash hands with soap and water after handling.
- Work clothes should be laundered separately.
- Launder contaminated clothing before re-use.
- Use good occupational work practice.
- Observe manufacturer's storing and handling recommendations.
- Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions are maintained.
RECOMMENDED STORAGE METHODS
- Polyethylene or polypropylene container.
- Packing as recommended by manufacturer
- Check all containers are clearly labeled and free from leaks.
STORAGE REQUIREMENTS
- Store in original containers.
- Keep containers securely sealed.
- Store in a cool, dry, well-ventilated area.
- Store away from incompatible materials and foodstuff containers.
- Protect containers against physical damage and check regularly for leaks.
- Observe manufacturer's storing and handling recommendations.
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From MSDS
Disposal Instructions
All waste must be handled in accordance with local, state and federal regulations.
- Recycle wherever possible or consult manufacturer for recycling options.
- Consult Waste Management Authority for disposal.
- Bury or incinerate residue at an approved site.
- Recycle containers if possible, or dispose of in an authorized landfill.
Puncture containers to prevent re-use and bury at an authorized landfill.
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Ingredients from MSDS/Label
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