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paclitaxel-loaded polymeric micelle A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer miceller nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity. Paclitaxel promotes microtubule assembly and prevents depolymerization, thus interfering with normal mitosis. The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20081005082709im_/http://www.nci.nih.gov/images/spacer.gif) | Genexol-PM | | ![](https://webarchive.library.unt.edu/eot2008/20081005082709im_/http://www.nci.nih.gov/images/spacer.gif) |
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