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Please Note: The technology listed below is not available to the public at this time. This technology is in the early stage of research and requires further development before it is ready for the marketplace. The VA is currently in the process of identifying potential companies who may be interested in licensing and/or further developing the technology through Cooperative Research and Development Agreements (CRADA). Through cooperative research initiatives such as these, it is our hope and goal that commercial products will be fully developed and made available to benefit veterans and others.  

VA TECHNOLOGY OPPORTUNITY BRIEF

Ventilation Feedback System

(#(01-082)

OPPORTUNITY: 
The Department of Veterans Affairs (VA) is seeking a commercial partner to further develop this technology through a Cooperative R&D Agreement (CRADA) to expedite bringing it to market.

BACKGROUND: 
It is estimated that 11.6 million persons are afflicted with asthma, 12 million with chronic bronchitis, and 2 million with emphysema. A recent study revealed that the prevalence of chronic bronchitis, airflow obstruction or both was 14% for men and 8% for women. Prevalence rates are strongly influenced by smoking and increasing age. Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States, and the mortality rate is expected to rise. Persons with COPD are more likely to rate their health as poor, to report more limitations in daily activities, to visit their physician, to stay in the hospital and to report more disability days. It was estimated that more than 17 million office visits and 2 million hospitalizations (> 13% of hospital visits) result from COPD. Exercise training is recognized as an important part of pulmonary rehabilitation. Innovative approaches to pulmonary rehabilitation are instrumental in modifying this cyclical pattern of increasing impairment and decreasing reserve to cope with the stress and strain of daily living.

TECHNOLOGY OVERVIEW: 
The invention is a computer system to be used in the therapy of chronic lung disease. The system measures the patient's breathing pattern by means of an airflow sensor attached to a mask or mouthpiece. With feedback and guidance from the system, the patient is taught to breathe during exertion in a way that helps to minimize some of the effects of the chronic lung disease. It is some patients' natural inclination to develop a breathing pattern characterized by a tendency to continuously over inflate their lungs with short and rapid breaths near the top of their lung capacity, particularly during exercise. These patients struggle to get an adequate breath, and continuously try to inhale more deeply even though part of their problem is that they are not exhaling deeply enough to get the breath they need. This invention helps the patient to learn a more useful pattern of breathing during exertion, by visually illustrating to the patient the time they spend in the inhaling and exhaling phases of their breathing cycle. The visual display graphically shows the "target" amount of exhalation time along with the actual measured times, and helps the patient keep score of their success in reaching specific targets.

TECHNICAL MERIT: 
The invention is an exercise training support system. The concept is developed with software written in C and C++. It is currently being ported to Visual C++ to run under Microsoft Windows™. The hardware of the prototype systems consists of a readily available personal computer, the venerable Fleisch pneumotachometer, and some connecting components. A technical advantage is that all of the components are available, well understood, and relatively inexpensive. The invention is in the prototype stage of development. The system has not been subjected to comparative studies with other methods of breathing pattern and exercise training. The invention was developed to assist in treating patients with COPD, including emphysema, chronic bronchitis, and asthma. There is some suggestion in the literature that resting BPT could have value in the management of congestive heart failure (Friedman 1999).

PATENT STATUS:

No patent was filed for this invention. The VA is currently seeking CRADA partners for this technology.

FOR MORE INFORMATION CONTACT:
Saleem Sheredos
Program Manager
Technology Transfer Program
Veterans Affairs
Office of Research & Development (12TT)
5th Floor
103 South Gay Street
Baltimore, MD 21202
202-380-5080
Fax 410.962.2141
e-mail: saleem.sheredos@va.gov