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Respirators as a Precaution for Hantavirus Infection

Update on the Nomenclature and Use of Respirators as a Precaution for Hantavirus Infection: February, 1999

half mask
a) half-mask air-purifying (or negative-pressure) respirator
The CDC "Hantavirus Pulmonary Syndrome--Updated Recommendations for Risk Reduction"(1)  describe precautions for persons who are involved in the cleanup of homes of confirmed cases of hantavirus infection or of areas with heavy rodent infestation and for workers in affected areas who are regularly exposed to rodents. Among these precautions is the wearing of one of the following types of respirators(2) equipped with a high-efficiency particulate air (HEPA) filter:


Recent changes in the nomenclature and certification of the type of filters used in these respirators include the discontinuation of the HEPA designation and the designation of new classes of filters.  As shown on the chart below, the N-100 (99.97) is equivalent to the previous HEPA filter.

powered air-purifying respirator
b) powered air-purifying respirator (PAPR)
Use of an N-100 filter should provide the same protection as the HEPA filter. Due to the nature of the virus, no studies have been able to test the efficacy of either the HEPA or N-100 filters in protecting against HPS transmission. Available evidence suggests that HPS is transmitted by inspiring small (less than 5 micron) viral particles in aerosols which the N-100 is the most effective in removing.

Cautions: As described in CDC "Hantavirus Pulmonary Syndrome--- Updated Recommendations for Risk Reduction", all negative-pressure respirators are fit-dependent. Anything that interferes with the respirator’s face seal, such as facial hair, will allow ambient air to bypass the filter medium in the respirator(3). Ideally, users should be fit-tested with the same make, model, style, and size of respirator that will be actually used. Respirator practices should follow a comprehensive user program and be supervised by a knowledgeable person.

 

New Classes of Filters for Respiratory Protection Devices(4)

New classes of filters †† Characteristics
  Equivalent to HEPA  
N-95 N-99 N-100 (99.97) Not resistant to oil
R-95 R-99 R-100 (99.97) Resistant to oil
P-95 P-99 P-100 (99.97) Oil Proof

†† number indicates % efficiency in removing monodispersed particles 0.3 micrometers in diameter.

Authority for testing and certifying these respirators has been given exclusively to NIOSH. For additional information:


(1) MMWR Recommendations and Reports, July 26, 2002; 51[RR-9]

(2) All of these respirators can be purchased from commercial suppliers of laboratory safety equipment.  The items displayed here are intended to show the general design of the respirator and do not constitute endorsement of any particular brand of respirator.

(3) MMWR 47(40): 1045-1049, demonstrates importance of fit testing for all negative-pressure respirators.

(4) As described in NIOSH 42, CFR 84.


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This page last reviewed Thursday, December 30, 2004

Special Pathogens Branch
Division of Viral and Rickettsial Diseases
National Center for Infectious Diseases
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