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Agent Name n-Butyl acetate
Alternative Name Butyl acetate
CAS Number 123-86-4
Formula C6-H12-O2
Major Category Solvents
Synonyms 1-Butyl acetate; Acetate de butyle [French]; Acetic acid n-butyl ester; Acetic acid, butyl ester; Butile (acetati di) [Italian]; Butyl acetate; Butyl ethanoate; Butylacetat [German]; Butylacetaten [Dutch]; Butyle (acetate de) [French]; Butylester kyseliny octove [Czech]; Octan n-butylu [Polish]; n-Butyl acetate; n-Butyl acetate (natural); n-Butyl ethanoate; [ChemIDplus] UN1123
Category Esters
Description Colorless liquid with a fruity odor; [NIOSH]
Sources/Uses Used in the manufacture of lacquers and plastics; [ACGIH]
Comments Narcosis induced in acute animal studies; [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 150 ppm
STEL (ACGIH) 200 ppm
PEL (OSHA) 150 ppm
MAK 100 ppm
IDLH (NIOSH) 1700 ppm
Excerpts from Documentation for IDLHs Other animal data: A 4�hour exposure to 10,000 ppm was not lethal to rats [Smyth 1956]. Human data: Severe irritation of the throat has been reported in volunteers exposed to 300 ppm for 3 to 5 minutes [Nelson et al. 1943]. However, it has also been reported that irritation of the eyes and nose is first objectionable at 3,300 ppm and that higher concentrations cause tearing and hyperemia of the conjunctiva [Grant 1974]
Vapor Pressure 11.5 mm Hg
Odor Threshold Low 0.06 ppm
Odor Threshold High 7.4 ppm
Lethal Concentration LC50 (rats) = 390 ppm/4H
Explanatory Notes IDLH = 10% LEL (lower explosive limit); Detection odor threshold from AIHA (mean = 0.31 ppm); Flash point = 22 deg C;
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: N-BUTYL ACETATE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: September, 2008