National Toxicology Program

Items received in response to the request for public comment in the Federal Register Notice (71 FR 18341-18345 April 11, 2006) and clarification (71 FR 23931 April 25, 2006):

• Arbutin
• tert-Butylacrylamide
• Ceric Oxide
• Diazonaphthoquinone derivatives:
  • Sodium 1,2-naphthoquinone- 2-diazide-5-sulfonate
  • 2,3,4-Trihydroxybenxophenone tris(1,2-naphthoquinonediazide- 5-sulfonate
  • 2,3,4-Trihydroxybenzophenone 1,2-naphthoquinonediazide-5- sulfonate
• 3-Dimethylaminopropyl methacrylamide
• Flame Retardants:
  • Antimony trioxide
  • Decabromodiphenyl oxide
  • Tris(chloropropyl)phosphate, mixture of four isomers)
  • Phosphonic acid, (3-((hydroxymethyl)amino)-3- oxopropyl)-,dimethyl ester
  • Tris(hydroxymethyl)phosphine oxide
  • Aromatic Phosphates:
    • tert-Butylphenyl diphenyl phosphate
    • 2-Ethylhexyl diphenyl phosphate
    • Isodecyl diphenyl phosphate
    • Phenol, isopropylated, phosphate (3:1)
    • Tricresyl phosphate
    • Triphenyl phosphate
• Gypsum, natural and synthetic forms
• N-methyl-3-oxobutanamide

Substances for Which No Study is Recommended at this Time:

• Phenoxethyl acrylate
• Trifluoromethylbenzene

The NTP invites interested parties to submit written comments or supplementary information on the nominated substances and study recommendations that appear here. The NTP welcomes toxicology and carcinogenesis study information from completed, ongoing, or anticipated studies, as well as information on current U.S. production levels, use or consumption patterns, human exposure, environmental occurrence, or public health concerns for any of the nominated substances. The NTP is interested in identifying appropriate animal and non-animal experimental models for mechanistic-based research, including genetically modified rodents and higher-throughput in vitro test methods, and as such, solicits comments regarding the use of specific in vivo and in vitro experimental approaches to address questions relevant to the nominated substances and issues under consideration. The NTP Board of Scientific Counselors (BSC) will discuss the nominations listed here at a public meeting on June 13, 2006. A separate Federal Register notice will be published in the future about this meeting. Comments or additional information may be submitted at any time; however, to ensure adequate time for consideration prior to the June 13, 2006 BSC meeting, comments should be submitted by May 10, 2006.

The NTP will not respond to submitted comments; however, all information received will be become part of the official record that the NTP considers in its ongoing review of these nominations. Persons submitting comments should include their name, affiliation, mailing address, phone, fax, e-mail address, and sponsoring organization (if any) with the submission. Written submissions will be made publicly available electronically on the NTP website as they are received.

Correspondence should be addressed to:
Dr. Scott A. Masten, Director
Office of Chemical Nomination and Selection
NIEHS/NTP

P.O. Box 12233, MD A3-07
111 T.W. Alexander Drive
Research Triangle Park, NC 27709
(919) 541-5710 (voice)
(919) 541-3647 (fax)

[ Send Email ]