| Agent Name |
Cyclonite |
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| Alternative Name |
RDX |
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| CAS Number |
121-82-4 |
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| Formula |
C3-H6-N6-O6 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
Cyclotrimethylenetrinitramine; Hexahydro-1,3,5-trinitro-s-triazine; Trimethylenetrinitramine; 1,3,5-Trinitro-1,3,5-triazacyclohexane; RDX; [NIOSH] UN0391 |
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| Category |
Explosives |
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| Description |
White, crystalline powder. [Note: A powerful high explosive.] [NIOSH] |
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| Sources/Uses |
Used as an explosive and rodenticide; [ACGIH] |
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| Comments |
In subchronic feeding studies of dogs (50 mg/kg/day for 6 weeks), one of seven dogs died, and the others had weight loss and seizures. Methemoglobinemia was not reported. Animals in chronic studies show liver injury. Workers have experienced central nervous system effects including seizures after occupational exposure. [ACGIH] |
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| Restricted |
Transportation forbidden for Cyclonite; Transportation forbidden by passenger aircraft/rail and cargo aircraft for Cyclonite (desensitized or wetted with >15% water; [HMT] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
0.5 mg/m3 |
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| Vapor Pressure |
4.1 x 10 -09 mm Hg |
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| Reference Link |
ATSDR - ToxFAQs - RDX (Cyclonite) |
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| Adverse Effects |
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| Neurotoxin |
Other CNS Neurotoxin |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CYCLONITE
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