Agent Name |
Dimethylamine |
CAS Number |
124-40-3 |
Formula |
C2-H7-N |
Major Category |
Nitrogen Compounds |
Synonyms |
Dimethylamine; Dimethylamine (anhydrous); Methanamine, N-methyl-; N,N-Dimethylamine; N-Methylmethanamine; [ChemIDplus] UN1032; UN1160 |
Category |
Amines, Aliphatic |
Description |
Colorless gas with an ammonia- or fish-like odor; Note: A liquid below 44 degrees F. Shipped as a liquefied compressed gas; [NIOSH] |
Sources/Uses |
Used as an accelerator in the manufacturing of rubber, detergents, and pesticides; Used in leather tanning; [Merck Index # 3228] Used in electroplating, epoxy resin curing, textile manufacturing, photographic processing, hide dehairing, and pharmaceutical production; [HSDB] |
Comments |
Liquid causes first degree burns on short exposure; [CHRIS] Corrosive to skin; [Quick CPC] Concentrations above 5420 ppm are lethal to mice with pulmonary hemorrhages and peripheral emphysema on pathological examination. [ACGIH] Pulmonary edema may result from inhalation of high concentrations. [NJ-HSFS] A lachrymator; [CHEMINFO] Animals suffer liver injury in high-dose experiments. [HSDB] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
5 ppm |
STEL (ACGIH) |
15 ppm |
PEL (OSHA) |
10 ppm |
MAK |
2 ppm |
IDLH (NIOSH) |
500 ppm |
Excerpts from Documentation for IDLHs |
Basis for revised IDLH: The revised IDLH for dimethylamine is 500 ppm based on acute inhalation toxicity data in animals [Steinhagen et al. 1982]. |
Vapor Pressure |
1297 mm Hg |
Odor Threshold Low |
0.00076 ppm |
Odor Threshold High |
1.6 ppm |
RD50 |
511 ppm |
Lethal Concentration |
LC50 (rats) = 4,540 ppm/6H |
Explanatory Notes |
Odor threshold from AIHA; The Guide from the Emergency Response Guidebook is for anhydrous dimethylamine. Flash point = 20 deg F; |
Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
Flammability (NFPA) |
4: burns readily |
Adverse Effects |
Toxic Pneumonitis |
Yes |
Dermatotoxin |
Skin Burns |
Lacrimator |
Yes |
Hepatotoxin |
Hepatotoxin, Secondary |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIMETHYLAMINE
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