National Toxicology Program

Items received in response to the request for public comment in the March 29, 2007 Federal Register Notice (72 FR 14816):

• Aminopyridines
  • 2-Aminopyridine
  • 3-Aminopyridine
  • 4-Aminopyridine
• Artificial butter flavoring mixture and certain components
  • Acetoin
  • Diacetyl
• Asbestos, naturally occurring and atypical forms
• Diethyl phthalate
• 2',2'''-Dithiobisbenzanilide
• 2-Methoxy-4-nitroaniline
• Nanoscale materials
  • Nanoscale gold
  • Nanoscale silver
• o-Phthalaldehyde

Substances for Which No Study is Recommended at this Time:

• Pentaethylenehexamine

The NTP invites interested parties to submit written comments or supplementary information on the nominated substances and study recommendations that appear in Table 1. The NTP welcomes toxicology study information from completed, ongoing, or anticipated studies, as well as information on current U.S. production levels, use or consumption patterns, human exposure, environmental occurrence, or public health concerns for any of the nominated substances. The NTP is interested in identifying appropriate animal and non-animal experimental models for mechanistic-based research, including genetically modified rodents and high-throughput in vitro test methods, and as such, solicits comments regarding the use of specific in vivo and in vitro experimental approaches to address questions relevant to the nominated substances and issues under consideration. Comments should be submitted by May 10, 2007; however, the NTP welcomes comments or additional information on these study nominations at any time.

The NTP will not respond to submitted comments; however, all information received will be become part of the official record that the NTP considers in its ongoing review of these nominations. Persons submitting comments should include their name, affiliation, mailing address, phone, fax, e-mail address, and sponsoring organization (if any) with the submission. Written submissions will be made available on the NTP website here as they are received.

Correspondence should be addressed to:
Dr. Scott A. Masten
Director, Office of Chemical Nomination and Selection
Environmental Toxicology Program
National Institute of Environmental Health Sciences

P.O. Box 12233, MD A3-07
111 T.W. Alexander Drive
Research Triangle Park, NC 27709
(919) 541-5710 (voice)
(919) 541-3647 (fax)

[ Send Email ]