U.S. Department of Defense

Congressionally-Directed Medical Research Program (CDMRP)

The following CDMRP Gulf War Veterans’ Illnesses Research Program (GWVIRP) projects were funded in late 2007.

Project No.

Project Title

DOD-GW060012

Structural MRI and Cognitive Correlates in Pest-Control Personnel from Gulf War I. This follow-up brain imaging study will evaluate the combination of exposures such as pesticides as possible factors for continued symptoms in Gulf War veterans.

DOD-GW060036

Q10 for Gulf War Veterans. This project will determine if administering coenzyme Q10 (Q10) to Gulf War veterans reduces their symptoms and improves their health.

DOD-GW060044

CNDP1 Polymorphisms and Carnosine Therapy in GWI. This project will test for possible genetic indicators of Gulf War Illness (GWI).

DOD-GW060048

A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial of Mifepristone in Gulf War Veterans with Chronic Multisymptom Illness. This study will test to determine if mifepristone improves the health of Gulf War veterans with chronic multisymptom illness (CMI).

DOD-GW060050

Autonomic Biomarkers and Treatment for Gulf War Illness. This project will attempt to shed light on the mechanisms of Gulf War illness and test drugs that might lead to effective treatments.

DOD-GW060053

Novel Pharmacological Approaches for Treatment of Neurotoxicity Induced by Chronic Exposure to Depleted Uranium. This animal study will look at potential treatments for neurotoxicity caused by chronic exposure to depleted uranium.

DOD-GW060062

Studies on Axonal Transport in an Animal Model for Gulf War Syndrome. The proposed study will use a recently established animal model to determine if exposure to various chemicals such as pesticides, drugs to protect against nerve agents, and vaccines may contribute to nerve degeneration like in ALS.

DOD-GW060082

Randomized Trial of an Environmental Medicine Approach to Gulf War Veterans' Illness. This project will try to determine if the environmental medicine approach is able in relieve symptoms in ill Gulf War veterans.

DOD-GW060091

Analysis of Paraoxonase Status among US Navy Gulf War Veterans with Increased Postwar Symptoms, Psychological Morbidity and Medical Conditions. The purpose of this study is to gain a better understanding of the potential effects that pesticides and the use of PB tablets may have had on an individual's post-war health.