Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name Dimethyl disulfide
CAS Number 624-92-0
Formula C2-H6-S2
Major Category Other Classes
Synonyms 2,3-Dithiabutane; Dimethyl disulfide; Dimethyldisulfide; Disulfide, dimethyl; Methyldisulfide; Methyldithiomethane; [ChemIDplus] Methyl disulfide; Dimethyl disulphide; MDS; Methyldithiomethane; DMDS; 2,3-Dithiabutane; Methyl disulphide; [CHEMINFO]
Category Sulfur Compounds
Description Colorless, oily liquid with a garlic-like odor; [CAMEO] Strong, nauseating odor; [CHEMINFO]
Sources/Uses Used to as a chemical intermediate: [CAMEO] Released in Kraft pulping to make paper; Also used as a "gas well down hole process aid"; Proposed to replace methyl mercaptan as a jet fuel additive; [NTP] Occupational exposure also occurs at sewage treatment plants. It occurs naturally in many foods. [HSDB] Also used as a sulfiding agent in refineries, a solvent for sulfur, to reduce coke deposits in the petrochemical industry, an artificial flavoring agent, and a corrosion inhibitor; [CHEMINFO]
Comments A mild skin irritant, dimethyl disulfide is toxic by inhalation, skin absorption, and ingestion. Workers are warned by the nauseating odor, but those exposed to high concentrations may experience fatigue, dyspnea, and upper respiratory tract irritation. At lethal concentrations, animals suffer severe lung injury and paralysis of respiratory muscles. [CHEMINFO]
Exposure Assessment
Skin Designation (ACGIH) Yes
TLV (ACGIH) 0.5 ppm
Vapor Pressure 28.7 mm Hg
Odor Threshold Low 0.00078 ppm
Odor Threshold High 0.0036 ppm
Lethal Concentration LC50 (rats) = 15.85 mg/m3/2H
Explanatory Notes Odor threshold (detection) from CHEMINFO;
Adverse Effects
Toxic Pneumonitis Yes
Neurotoxin Other CNS Neurotoxin
Links to Other NLM Databases
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: January, 2009