| Agent Name |
Formamide |
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| CAS Number |
75-12-7 |
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| Formula |
C-H3-N-O |
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| Major Category |
Solvents |
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| Synonyms |
Amid kyseliny mravenci [Czech]; Carbamaldehyde; Formamide; Formic acid, amide; Formimidic acid; Methanamide; Methanoic acid, amide; [ChemIDplus] UN8027 |
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| Category |
Amides |
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| Description |
Colorless, oily liquid. [Note: A solid below 37 degrees F.]; [NIOSH] |
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| Sources/Uses |
Used as a chemical intermediate and ionizing solvent; also used as a softener for glues, gums, and paper; [ACGIH] |
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| Comments |
Subchronic studies of rats exposed at 1500 ppm show decreased weight gain, kidney injury, and suppression of platelets and lymphocytes. By analogy with dimethylformamide, formamide is a suspected liver toxin. [ACGIH] A skin and eye irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
10 ppm |
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| Vapor Pressure |
0.06 mm Hg |
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| Explanatory Notes |
Flash point = 310 deg F; |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: FORMAMIDE
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